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Cellosaurus RBL18 (CVCL_S619)

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Cell line name RBL18
Accession CVCL_S619
Resource Identification Initiative To cite this cell line use: RBL18 (RRID:CVCL_S619)
Comments Doubling time: 9 days (PubMed=2365495; DSMZ=ACC-913).
Derived from site: In situ; Eye; UBERON=UBERON_0000970.
Sequence variations
  • Mutation; HGNC; HGNC:9884; RB1; Simple; p.Met484Valfs*8 (c.1450_1451delAT); ClinVar=VCV000855427; Zygosity=Homozygous (DSMZ=ACC-913).
Disease Unilateral retinoblastoma (NCIt: C8714)
Retinoblastoma (ORDO: Orphanet_790)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 1Y3M
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-913

Markers:
AmelogeninX,Y
CSF1PO9,10
D2S133817,19
D3S135815,18
D5S81813
D7S82010
D8S117910,15
D13S31711
D16S53914
D18S5113,16
D19S43314,15
D21S1128,29
FGA19,24
Penta D13,16
Penta E11,13
TH019,10
TPOX8,11
vWA18,19

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Publications

PubMed=2090524; DOI=10.1111/j.1432-0436.1990.tb00479.x
Sabine Griegel, Kerstin Heise, Andrea Kindler-Rohrborn, Manfred Fedor Rajewsky;
In vitro differentiation of human retinoblastoma cells into neuronal phenotypes.
Differentiation 45:250-257(1990)

PubMed=2365495; DOI=10.1002/ijc.2910460123
Sabine Griegel, Chen Hong, Roland Frotschl, Dieter F. Hulser, Valerie Greger, Bernhard Horsthemke, Manfred Fedor Rajewsky;
Newly established human retinoblastoma cell lines exhibit an 'immortalized' but not an invasive phenotype in vitro.
Int. J. Cancer 46:125-132(1990)

PubMed=7959682; DOI=10.1007/BF00211013
Valerie Greger, Nils Debus, Dietmar R. Lohmann, Wolfgang Hopping, Eberhard Passarge, Bernhard Horsthemke;
Frequency and parental origin of hypermethylated RB1 alleles in retinoblastoma.
Hum. Genet. 94:491-496(1994)

Cross-references
Cell line collections (Providers) DSMZ; ACC-913
Cell line databases/resources DSMZCellDive; ACC-913
Encyclopedic resources Wikidata; Q54949355
Entry history
Entry creation03-Feb-2014
Last entry update19-Dec-2024
Version number14