ID   RBL18
AC   CVCL_S619
DR   DSMZ; ACC-913
DR   DSMZCellDive; ACC-913
DR   Wikidata; Q54949355
RX   PubMed=2090524;
RX   PubMed=2365495;
RX   PubMed=7959682;
CC   Doubling time: 9 days (PubMed=2365495; DSMZ=ACC-913).
CC   Sequence variation: Mutation; HGNC; HGNC:9884; RB1; Simple; p.Met484Valfs*8 (c.1450_1451delAT); ClinVar=VCV000855427; Zygosity=Homozygous (DSMZ=ACC-913).
CC   Derived from site: In situ; Eye; UBERON=UBERON_0000970.
ST   Source(s): DSMZ=ACC-913
ST   Amelogenin: X,Y
ST   CSF1PO: 9,10
ST   D13S317: 11
ST   D16S539: 14
ST   D18S51: 13,16
ST   D19S433: 14,15
ST   D21S11: 28,29
ST   D2S1338: 17,19
ST   D3S1358: 15,18
ST   D5S818: 13
ST   D7S820: 10
ST   D8S1179: 10,15
ST   FGA: 19,24
ST   Penta D: 13,16
ST   Penta E: 11,13
ST   TH01: 9,10
ST   TPOX: 8,11
ST   vWA: 18,19
DI   NCIt; C8714; Unilateral retinoblastoma
DI   ORDO; Orphanet_790; Retinoblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   1Y3M
CA   Cancer cell line
DT   Created: 03-02-14; Last updated: 19-12-24; Version: 14
//
RX   PubMed=2090524; DOI=10.1111/j.1432-0436.1990.tb00479.x;
RA   Griegel S., Heise K., Kindler-Rohrborn A., Rajewsky M.F.;
RT   "In vitro differentiation of human retinoblastoma cells into neuronal
RT   phenotypes.";
RL   Differentiation 45:250-257(1990).
//
RX   PubMed=2365495; DOI=10.1002/ijc.2910460123;
RA   Griegel S., Hong C., Frotschl R., Hulser D.F., Greger V.,
RA   Horsthemke B., Rajewsky M.F.;
RT   "Newly established human retinoblastoma cell lines exhibit an
RT   'immortalized' but not an invasive phenotype in vitro.";
RL   Int. J. Cancer 46:125-132(1990).
//
RX   PubMed=7959682; DOI=10.1007/BF00211013;
RA   Greger V., Debus N., Lohmann D.R., Hopping W., Passarge E.,
RA   Horsthemke B.;
RT   "Frequency and parental origin of hypermethylated RB1 alleles in
RT   retinoblastoma.";
RL   Hum. Genet. 94:491-496(1994).
//