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Cellosaurus WERI-Rb-27 (CVCL_S610)

[Text version]
Cell line name WERI-Rb-27
Synonyms WERI-Rb27; WERI-RB27; W-27; Wills Eye Research Institute-Retinoblastoma-27
Accession CVCL_S610
Resource Identification Initiative To cite this cell line use: WERI-Rb-27 (RRID:CVCL_S610)
Comments Problematic cell line: Contaminated. Shown to be a Y-79 derivative (PubMed=1679230). Originally thought to originate from a 2 year old boy with a bilateral retinoblastoma.
Population: Caucasian.
Doubling time: 1.9 days (PubMed=2391623).
Derived from site: In situ; Eye, globe; UBERON=UBERON_0010230.
Sequence variations
  • Mutation; HGNC; 9884; RB1; Unexplicit; Ex2-6del; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9884; RB1; Unexplicit; IVS20+1G>A; Zygosity=Heterozygous (from parent cell line).
Disease Retinoblastoma (NCIt: C7541)
Retinoblastoma (ORDO: Orphanet_790)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1893 (Y-79)
Sex of cell Female
Age at sampling 2Y6M
Category Cancer cell line

PubMed=2391623; DOI=10.3928/0191-3913-19900701-11
Sery T.W., Lee E.Y.-H.P., Lee W.-H., Bookstein R., Wong V., Shields J.A., Augsburger J.J., Donoso L.A.
Characteristics of two new retinoblastoma cell lines: WERI-Rb24 and WERI-Rb27.
J. Pediatr. Ophthalmol. Strabismus 27:212-217(1990)

PubMed=1679230; DOI=10.3109/13816819109023085
Madreperla S.A., Bookstein R., Jones O.W., Lee W.-H.
Retinoblastoma cell lines Y79, RB355 and WERI-Rb27 are genetically related.
Ophthalmic Paediatr. Genet. 12:49-56(1991)

Encyclopedic resources Wikidata; Q54993784
Entry history
Entry creation03-Feb-2014
Last entry update29-Jun-2023
Version number15