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Cellosaurus TtT/GF (CVCL_S512)

[Text version]

Cell line name TtT/GF
Accession CVCL_S512
Resource Identification Initiative To cite this cell line use: TtT/GF (RRID:CVCL_S512)
Comments Doubling time: 14.4 hours (PubMed=24881870).
Omics: Transcriptome analysis.
Derived from sampling site: Pituitary gland. Cell type=Folliculostellate cell.
Disease Mouse pituitary gland neoplasms (NCIt: C24037)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6N x C3H/2N.
Originate from same individual CVCL_U804 ! TtT/M-87
Category Cancer cell line

PubMed=1446645; DOI=10.1210/endo.131.6.1446645
Inoue K., Matsumoto H., Koyama C., Shibata K., Nakazato Y., Ito A.
Establishment of a folliculo-stellate-like cell line from a murine thyrotropic pituitary tumor.
Endocrinology 131:3110-3116(1992)

PubMed=8404665; DOI=10.1210/endo.133.5.8404665
Matsumoto H., Koyama C., Sawada T., Koike K., Hirota K., Miyake A., Arimura A., Inoue K.
Pituitary folliculo-stellate-like cell line (TtT/GF) responds to novel hypophysiotropic peptide (pituitary adenylate cyclase-activating peptide), showing increased adenosine 3',5'-monophosphate and interleukin-6 secretion and cell proliferation.
Endocrinology 133:2150-2155(1993)

PubMed=15541569; DOI=10.1016/j.mce.2004.07.018
Ooi G.T., Tawadros N., Escalona R.M.
Pituitary cell lines and their endocrine applications.
Mol. Cell. Endocrinol. 228:1-21(2004)

PubMed=23881407; DOI=10.1007/s00441-013-1686-7
Mitsuishi H., Kato T., Chen M., Cai L.Y., Yako H., Higuchi M., Yoshida S., Kanno N., Ueharu H., Kato Y.
Characterization of a pituitary-tumor-derived cell line, TtT/GF, that expresses Hoechst efflux ABC transporter subfamily G2 and stem cell antigen 1.
Cell Tissue Res. 354:563-572(2013)

PubMed=24881870; DOI=10.1262/jrd.2014-031
Yoshida S., Higuchi M., Ueharu H., Nishimura N., Tsuda M., Yako H., Chen M., Mitsuishi H., Sano Y., Kato T., Kato Y.
Characterization of murine pituitary-derived cell lines Tpit/F1, Tpit/E and TtT/GF.
J. Reprod. Dev. 60:295-303(2014)

Cell line collections RCB; RCB1279
Cell line databases/resources CLO; CLO_0050271
Encyclopedic resources Wikidata; Q54973295
Entry history
Entry creation03-Feb-2014
Last entry update15-Dec-2022
Version number7