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Cellosaurus TtT/GF (CVCL_S512)

[Text version]
Cell line name TtT/GF
Accession CVCL_S512
Resource Identification Initiative To cite this cell line use: TtT/GF (RRID:CVCL_S512)
Comments Doubling time: 14.4 hours (PubMed=24881870).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Pituitary gland; UBERON=UBERON_0000007.
Cell type: Folliculostellate cell; CL=CL_0000642.
Disease Mouse pituitary gland neoplasms (NCIt: C24037)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6N x C3H/2N.
Originate from same individual CVCL_U804 ! TtT/M-87
Category Cancer cell line
Publications

PubMed=1446645; DOI=10.1210/endo.131.6.1446645
Kinji Inoue, Hirokazu Matsumoto, Chiaki Koyama, Kinuko Shibata, Yoichi Nakazato, Akihiro Ito;
Establishment of a folliculo-stellate-like cell line from a murine thyrotropic pituitary tumor.
Endocrinology 131:3110-3116(1992)

PubMed=8404665; DOI=10.1210/endo.133.5.8404665
Hirokazu Matsumoto, Chiaki Koyama, Takeshi Sawada, Koji Koike, Kenji Hirota, Akira Miyake, Akira Arimura, Kinji Inoue;
Pituitary folliculo-stellate-like cell line (TtT/GF) responds to novel hypophysiotropic peptide (pituitary adenylate cyclase-activating peptide), showing increased adenosine 3',5'-monophosphate and interleukin-6 secretion and cell proliferation.
Endocrinology 133:2150-2155(1993)

PubMed=15541569; DOI=10.1016/j.mce.2004.07.018
Guck T. Ooi, Neveen Tawadros, Ruth M. Escalona;
Pituitary cell lines and their endocrine applications.
Mol. Cell. Endocrinol. 228:1-21(2004)

PubMed=23881407; DOI=10.1007/s00441-013-1686-7
Hideo Mitsuishi, Takako Kato, Mo Chen, Li-Yi Cai, Hideji Yako, Masashi Higuchi, Saishu Yoshida, Naoko Kanno, Hiroki Ueharu, Yukio Kato;
Characterization of a pituitary-tumor-derived cell line, TtT/GF, that expresses Hoechst efflux ABC transporter subfamily G2 and stem cell antigen 1.
Cell Tissue Res. 354:563-572(2013)

PubMed=24881870; DOI=10.1262/jrd.2014-031; PMCID=PMC4139504
Saishu Yoshida, Masashi Higuchi, Hiroki Ueharu, Naoto Nishimura, Mitsuyoshi Tsuda, Hideji Yako, Mo Chen, Hideo Mitsuishi, Yoshiya Sano, Takako Kato, Yukio Kato;
Characterization of murine pituitary-derived cell lines Tpit/F1, Tpit/E and TtT/GF.
J. Reprod. Dev. 60:295-303(2014)

Cross-references
Cell line collections (Providers) RCB; RCB1279
Cell line databases/resources CLO; CLO_0050271
Encyclopedic resources Wikidata; Q54973295
Entry history
Entry creation03-Feb-2014
Last entry update10-Apr-2025
Version number10