ID   TtT/GF
AC   CVCL_S512
DR   CLO; CLO_0050271
DR   RCB; RCB1279
DR   Wikidata; Q54973295
RX   PubMed=1446645;
RX   PubMed=8404665;
RX   PubMed=15541569;
RX   PubMed=23881407;
RX   PubMed=24881870;
CC   Doubling time: 14.4 hours (PubMed=24881870).
CC   Omics: Transcriptomics; Microarray.
CC   Derived from site: In situ; Pituitary gland; UBERON=UBERON_0000007.
CC   Cell type: Folliculostellate cell; CL=CL_0000642.
CC   Breed/subspecies: C57BL/6N x C3H/2N.
DI   NCIt; C24037; Mouse pituitary gland neoplasms
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
OI   CVCL_U804 ! TtT/M-87
CA   Cancer cell line
DT   Created: 03-02-14; Last updated: 10-04-25; Version: 10
//
RX   PubMed=8404665; DOI=10.1210/endo.133.5.8404665;
RA   Matsumoto, Hirokazu
RA   Koyama, Chiaki
RA   Sawada, Takeshi
RA   Koike, Koji
RA   Hirota, Kenji
RA   Miyake, Akira
RA   Arimura, Akira
RA   Inoue, Kinji
RT   "Pituitary folliculo-stellate-like cell line (TtT/GF) responds to
RT   novel hypophysiotropic peptide (pituitary adenylate cyclase-activating
RT   peptide), showing increased adenosine 3',5'-monophosphate and
RT   interleukin-6 secretion and cell proliferation.";
RL   Endocrinology 133:2150-2155(1993).
//
RX   PubMed=24881870; DOI=10.1262/jrd.2014-031; PMCID=PMC4139504;
RA   Yoshida, Saishu
RA   Higuchi, Masashi
RA   Ueharu, Hiroki
RA   Nishimura, Naoto
RA   Tsuda, Mitsuyoshi
RA   Yako, Hideji
RA   Chen, Mo
RA   Mitsuishi, Hideo
RA   Sano, Yoshiya
RA   Kato, Takako
RA   Kato, Yukio
RT   "Characterization of murine pituitary-derived cell lines Tpit/F1,
RT   Tpit/E and TtT/GF.";
RL   J. Reprod. Dev. 60:295-303(2014).
//
RX   PubMed=1446645; DOI=10.1210/endo.131.6.1446645;
RA   Inoue, Kinji
RA   Matsumoto, Hirokazu
RA   Koyama, Chiaki
RA   Shibata, Kinuko
RA   Nakazato, Yoichi
RA   Ito, Akihiro
RT   "Establishment of a folliculo-stellate-like cell line from a murine
RT   thyrotropic pituitary tumor.";
RL   Endocrinology 131:3110-3116(1992).
//
RX   PubMed=15541569; DOI=10.1016/j.mce.2004.07.018;
RA   Ooi, Guck T.
RA   Tawadros, Neveen
RA   Escalona, Ruth M.
RT   "Pituitary cell lines and their endocrine applications.";
RL   Mol. Cell. Endocrinol. 228:1-21(2004).
//
RX   PubMed=23881407; DOI=10.1007/s00441-013-1686-7;
RA   Mitsuishi, Hideo
RA   Kato, Takako
RA   Chen, Mo
RA   Cai, Li-Yi
RA   Yako, Hideji
RA   Higuchi, Masashi
RA   Yoshida, Saishu
RA   Kanno, Naoko
RA   Ueharu, Hiroki
RA   Kato, Yukio
RT   "Characterization of a pituitary-tumor-derived cell line, TtT/GF, that
RT   expresses Hoechst efflux ABC transporter subfamily G2 and stem cell
RT   antigen 1.";
RL   Cell Tissue Res. 354:563-572(2013).
//