ID   TtT/GF
AC   CVCL_S512
DR   CLO; CLO_0050271
DR   RCB; RCB1279
DR   Wikidata; Q54973295
RX   PubMed=1446645;
RX   PubMed=8404665;
RX   PubMed=15541569;
RX   PubMed=23881407;
RX   PubMed=24881870;
CC   Doubling time: 14.4 hours (PubMed=24881870).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Pituitary gland; UBERON=UBERON_0000007.
CC   Cell type: Folliculostellate cell; CL=CL_0000642.
CC   Breed/subspecies: C57BL/6N x C3H/2N.
DI   NCIt; C24037; Mouse pituitary gland neoplasms
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
OI   CVCL_U804 ! TtT/M-87
CA   Cancer cell line
DT   Created: 03-02-14; Last updated: 29-06-23; Version: 9
//
RX   PubMed=1446645; DOI=10.1210/endo.131.6.1446645;
RA   Inoue K., Matsumoto H., Koyama C., Shibata K., Nakazato Y., Ito A.;
RT   "Establishment of a folliculo-stellate-like cell line from a murine
RT   thyrotropic pituitary tumor.";
RL   Endocrinology 131:3110-3116(1992).
//
RX   PubMed=8404665; DOI=10.1210/endo.133.5.8404665;
RA   Matsumoto H., Koyama C., Sawada T., Koike K., Hirota K., Miyake A.,
RA   Arimura A., Inoue K.;
RT   "Pituitary folliculo-stellate-like cell line (TtT/GF) responds to
RT   novel hypophysiotropic peptide (pituitary adenylate cyclase-activating
RT   peptide), showing increased adenosine 3',5'-monophosphate and
RT   interleukin-6 secretion and cell proliferation.";
RL   Endocrinology 133:2150-2155(1993).
//
RX   PubMed=15541569; DOI=10.1016/j.mce.2004.07.018;
RA   Ooi G.T., Tawadros N., Escalona R.M.;
RT   "Pituitary cell lines and their endocrine applications.";
RL   Mol. Cell. Endocrinol. 228:1-21(2004).
//
RX   PubMed=23881407; DOI=10.1007/s00441-013-1686-7;
RA   Mitsuishi H., Kato T., Chen M., Cai L.-Y., Yako H., Higuchi M.,
RA   Yoshida S., Kanno N., Ueharu H., Kato Y.;
RT   "Characterization of a pituitary-tumor-derived cell line, TtT/GF, that
RT   expresses Hoechst efflux ABC transporter subfamily G2 and stem cell
RT   antigen 1.";
RL   Cell Tissue Res. 354:563-572(2013).
//
RX   PubMed=24881870; DOI=10.1262/jrd.2014-031;
RA   Yoshida S., Higuchi M., Ueharu H., Nishimura N., Tsuda M., Yako H.,
RA   Chen M., Mitsuishi H., Sano Y., Kato T., Kato Y.;
RT   "Characterization of murine pituitary-derived cell lines Tpit/F1,
RT   Tpit/E and TtT/GF.";
RL   J. Reprod. Dev. 60:295-303(2014).
//