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Cellosaurus PIG1 (CVCL_S410)

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Cell line name PIG1
Synonyms PIGI
Accession CVCL_S410
Resource Identification Initiative To cite this cell line use: PIG1 (RRID:CVCL_S410)
Comments Doubling time: 1.16 days (PubMed=10937834).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
Cell type: Melanocyte of foreskin; CL=CL_2000045.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_E5FB (Mf9013)
Sex of cell Male
Age at sampling 2Y
Category Transformed cell line
STR profile Source(s): ATCC=CRL-2208

Markers:
AmelogeninX
CSF1PO10,12
D5S81812,13
D7S8208,10
D13S3178,11
D16S5398,11
TH016,7
TPOX8
vWA17

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Publications

PubMed=9028834; DOI=10.1007/s11626-997-0021-6
Isabelle Caroline Le Poole, Frank M. van den Berg, Rene M.J.G.J. van den Wijngaard, Denise A. Galloway, Peter J. van Amstel, Anita A.M. Buffing, Henk L. Smits, Wiete Westerhof, Pranab K. Das;
Generation of a human melanocyte cell line by introduction of HPV16 E6 and E7 genes.
In Vitro Cell. Dev. Biol. Anim. 33:42-49(1997)

PubMed=10937834; DOI=10.1290/1071-2690(2000)036<0309:PAIHVM>2.0.CO;2
Isabelle Caroline Le Poole, Raymond E. Boissy, Rangaprasad Sarangarajan, Jing Chen, Judith J. Forristal, Pranav Sheth, Wiete Westerhof, George Babcock, Pranab K. Das, Catharine B. Saelinger;
PIG3V, an immortalized human vitiligo melanocyte cell line, expresses dilated endoplasmic reticulum.
In Vitro Cell. Dev. Biol. Anim. 36:309-319(2000)

PubMed=18594937; DOI=10.1007/s11626-008-9113-1
Krassimira Ivanova, Britta Lambers, Rene M.J.G.J. van den Wijngaard, Isabelle Caroline Le Poole, Olga Grigorieva, Rupert Gerzer, Pranab K. Das;
Immortalization of human melanocytes does not alter the de novo properties of nitric oxide to induce cell detachment from extracellular matrix components via cGMP.
In Vitro Cell. Dev. Biol. Anim. 44:385-395(2008)

Cross-references
Cell line collections (Providers) ATCC; CRL-2208 - Discontinued
CancerTools; 154099
Biological sample resources BioSample; SAMN03472565
Encyclopedic resources Wikidata; Q54947405
Entry history
Entry creation05-Nov-2013
Last entry update14-Aug-2025
Version number21