ID   PIG1
AC   CVCL_S410
SY   PIGI
DR   ATCC; CRL-2208
DR   BioSample; SAMN03472565
DR   CancerTools; 154099
DR   Wikidata; Q54947405
RX   PubMed=9028834;
RX   PubMed=10937834;
RX   PubMed=18594937;
CC   Doubling time: 1.16 days (PubMed=10937834).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Discontinued: ATCC; CRL-2208; true.
CC   Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
CC   Cell type: Melanocyte of foreskin; CL=CL_2000045.
ST   Source(s): ATCC=CRL-2208
ST   Amelogenin: X
ST   CSF1PO: 10,12
ST   D13S317: 8,11
ST   D16S539: 8,11
ST   D5S818: 12,13
ST   D7S820: 8,10
ST   TH01: 6,7
ST   TPOX: 8
ST   vWA: 17
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_E5FB ! Mf9013
SX   Male
AG   2Y
CA   Transformed cell line
DT   Created: 05-11-13; Last updated: 10-04-25; Version: 20
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RX   PubMed=9028834; DOI=10.1007/s11626-997-0021-6;
RA   Le Poole I.C., van den Berg F.M., van den Wijngaard R.M.J.G.J.,
RA   Galloway D.A., van Amstel P.J., Buffing A.A.M., Smits H.L.,
RA   Westerhof W., Das P.K.;
RT   "Generation of a human melanocyte cell line by introduction of HPV16
RT   E6 and E7 genes.";
RL   In Vitro Cell. Dev. Biol. Anim. 33:42-49(1997).
//
RX   PubMed=10937834; DOI=10.1290/1071-2690(2000)036<0309:PAIHVM>2.0.CO;2;
RA   Le Poole I.C., Boissy R.E., Sarangarajan R., Chen J., Forristal J.J.,
RA   Sheth P., Westerhof W., Babcock G., Das P.K., Saelinger C.B.;
RT   "PIG3V, an immortalized human vitiligo melanocyte cell line, expresses
RT   dilated endoplasmic reticulum.";
RL   In Vitro Cell. Dev. Biol. Anim. 36:309-319(2000).
//
RX   PubMed=18594937; DOI=10.1007/s11626-008-9113-1;
RA   Ivanova K., Lambers B., van den Wijngaard R.M.J.G.J., Le Poole I.C.,
RA   Grigorieva O., Gerzer R., Das P.K.;
RT   "Immortalization of human melanocytes does not alter the de novo
RT   properties of nitric oxide to induce cell detachment from
RT   extracellular matrix components via cGMP.";
RL   In Vitro Cell. Dev. Biol. Anim. 44:385-395(2008).
//