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Cellosaurus HEp2-Mx2/EGFP L1D7 (CVCL_RX04)

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Cell line name HEp2-Mx2/EGFP L1D7
Synonyms HEp L1D7
Accession CVCL_RX04
Resource Identification Initiative To cite this cell line use: HEp2-Mx2/EGFP L1D7 (RRID:CVCL_RX04)
Comments Problematic cell line: Contaminated. Parent cell line (HEp-2) has been shown to be a HeLa derivative.
Population: African American.
Biotechnology: Used for a reporter gene assay (RGA) of the human type 1 interferon potency.
Characteristics: Expression of eGFP is under the control of the control of the mouse Mx2 promoter.
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1906 (HEp-2)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line

PubMed=22373148; DOI=10.1186/1753-6561-5-S8-P4
Burgi M., Prieto C., Oggero M., Bollati-Fogolin M., Etcheverrigaray M., Kratje R.
New reporter cell clones to determine the biological activity of human type I interferons.
BMC Proc. 5 Suppl. 8:P4-P4(2011)

Encyclopedic resources Wikidata; Q54882750
Entry history
Entry creation05-Mar-2018
Last entry update05-Oct-2023
Version number7