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Cellosaurus HepJ5 (CVCL_RW48)

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Cell line name HepJ5
Synonyms Hep-J5; Hep J5
Accession CVCL_RW48
Resource Identification Initiative To cite this cell line use: HepJ5 (RRID:CVCL_RW48)
Comments Population: Caucasian.
Characteristics: GRP78-overexpressing.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=19830497; DOI=10.1245/s10434-009-0718-8
Jeng-Fong Chiou, Cheng-Jeng Tai, Ming-Te Huang, Po-Li Wei, Yu-Huei Wang, Jane An, Chih-Hsiung Wu, Tsan-Zon Liu, Yu-Jia Chang;
Glucose-regulated protein 78 is a novel contributor to acquisition of resistance to sorafenib in hepatocellular carcinoma.
Ann. Surg. Oncol. 17:603-612(2010)

PubMed=20087778; DOI=10.1245/s10434-010-0912-8
Yu-Jia Chang, Chong-Chi Chiu, Chih-Hsiung Wu, Jane An, Cheng-Chia Wu, Tsan-Zon Liu, Po-Li Wei, Ming-Te Huang;
Glucose-regulated protein 78 (GRP78) silencing enhances cell migration but does not influence cell proliferation in hepatocellular carcinoma.
Ann. Surg. Oncol. 17:1703-1709(2010)

Cross-references
Cell line databases/resources cancercelllines; CVCL_RW48
Encyclopedic resources Wikidata; Q54882869
Entry history
Entry creation05-Mar-2018
Last entry update19-Dec-2024
Version number12