Cellosaurus cell line V79 SPD8 (CVCL

Cellosaurus V79 SPD8 (CVCL_RW42)

Cross-references
Cell line name	V79 SPD8
Synonyms	V79/SPD8; V79(SPD8); SPD8; SPD8/V79
Accession	CVCL_RW42
Resource Identification Initiative	To cite this cell line use: V79 SPD8 (RRID:CVCL_RW42)
Comments	Selected for resistance to: ChEBI; CHEBI_9555; Tioguanine (6-thioguanine; 6-TG). Derived from site: In situ; Lung; UBERON=UBERON_0002048. Cell type: Fibroblast of lung; CL=CL_0002553.
Sequence variations	Mutation; UniProtKB; P00494; Hprt1; Unexplicit; Ex7dup; Zygosity=Unspecified (PubMed=8914605). Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line). Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
Species of origin	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy	Parent: CVCL_2234 (V79)
Sex of cell	Male
Age at sampling	Adult
Category	Spontaneously immortalized cell line
Publications	PubMed=8914605; DOI=10.1007/BF02369910 Elisabetta Dare, Li-Hua Zhang, Dag Jenssen; Characterization of mutants involving partial exon duplications in the hprt gene of Chinese hamster V79 cells. Somat. Cell Mol. Genet. 22:201-210(1996) PubMed=9642052; DOI=10.1006/jmbi.1998.1809 Thomas Helleday, Catherine Arnaudeau, Dag Jenssen; A partial hprt gene duplication generated by non-homologous recombination in V79 Chinese hamster cells is eliminated by homologous recombination. J. Mol. Biol. 279:687-694(1998) PubMed=10373364; DOI=10.1006/jmbi.1999.2856 Catherine Arnaudeau, Thomas Helleday, Dag Jenssen; The RAD51 protein supports homologous recombination by an exchange mechanism in mammalian cells. J. Mol. Biol. 289:1231-1238(1999)
Encyclopedic resources	Wikidata; Q54992582
Entry history
Entry creation	05-Mar-2018
Last entry update	19-Dec-2024
Version number	10