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Cellosaurus V79 SP5 (CVCL_RW41)

[Text version]
Cell line name V79 SP5
Synonyms V79 Sp5; V79/SP5; SP5; Sp5; SP5/V79
Accession CVCL_RW41
Resource Identification Initiative To cite this cell line use: V79 SP5 (RRID:CVCL_RW41)
Comments Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Cell type: Fibroblast of lung; CL=CL_0002553.
Sequence variations
  • Mutation; UniProtKB; P00494; Hprt1; Unexplicit; Ex2dup; Zygosity=Unspecified (PubMed=1576714).
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Leu133Gln (c.398T>A); Zygosity=Unspecified (from parent cell line).
  • Mutation; UniProtKB; O09185; Tp53; Simple; p.Cys135Trp (c.405C>G); Zygosity=Unspecified (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_2234 (V79)
Sex of cell Male
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=2471930; DOI=10.1016/0027-5107(89)90076-6
Zhang L.-H., Jenssen D.
Isolation and characterization of spontaneously occurring mutations at the HPRT locus in V79 Chinese hamster cells.
Mutat. Res. 212:253-262(1989)

PubMed=1576714; DOI=10.1093/carcin/13.4.609
Zhang L.-H., Jenssen D.
Reversion of the hprt mutant clone SP5 by intrachromosomal recombination.
Carcinogenesis 13:609-615(1992)

PubMed=7955071; DOI=10.1093/carcin/15.10.2303
Zhang L.-H., Jenssen D.
Studies on intrachromosomal recombination in SP5/V79 Chinese hamster cells upon exposure to different agents related to carcinogenesis.
Carcinogenesis 15:2303-2310(1994)

PubMed=8914605; DOI=10.1007/BF02369910
Dare E., Zhang L.-H., Jenssen D.
Characterization of mutants involving partial exon duplications in the hprt gene of Chinese hamster V79 cells.
Somat. Cell Mol. Genet. 22:201-210(1996)

Cross-references
Encyclopedic resources Wikidata; Q54992579
Entry history
Entry creation05-Mar-2018
Last entry update29-Jun-2023
Version number9