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Cellosaurus SV-589 (CVCL_RW34)

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Cell line name SV-589
Synonyms SV589
Accession CVCL_RW34
Resource Identification Initiative To cite this cell line use: SV-589 (RRID:CVCL_RW34)
Comments Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Omics: Phenotyping; CRISPR screening.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C8YJ (SV589j)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=6091915; DOI=10.1016/0092-8674(84)90188-0
Tokuo Yamamoto, C. Geoffrey Davis, Michael Stuart Brown, Wolfgang J. Schneider, M. Linette Casey, Joseph Leonard Goldstein, David W. Russell;
The human LDL receptor: a cysteine-rich protein with multiple Alu sequences in its mRNA.
Cell 39:27-38(1984)

PubMed=32690708; DOI=10.1073/pnas.2010682117; PMCID=PMC7414171
Michael N. Trinh, Michael Stuart Brown, Joseph Leonard Goldstein, Jaeil Han, Goncalo Vale, Jeffrey G. McDonald, Joachim Seemann, Joshua T. Mendell, Fei-Ran Lu;
Last step in the path of LDL cholesterol from lysosome to plasma membrane to ER is governed by phosphatidylserine.
Proc. Natl. Acad. Sci. U.S.A. 117:18521-18529(2020)

Cross-references
Encyclopedic resources Wikidata; Q54970925
Entry history
Entry creation05-Mar-2018
Last entry update10-Apr-2025
Version number8