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Cellosaurus SV589j (CVCL_C8YJ)

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Cell line name SV589j
Accession CVCL_C8YJ
Resource Identification Initiative To cite this cell line use: SV589j (RRID:CVCL_C8YJ)
Comments Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Omics: Phenotyping; CRISPR screening.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_RW34 (SV-589)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=32690708; DOI=10.1073/pnas.2010682117; PMCID=PMC7414171
Michael N. Trinh, Michael Stuart Brown, Joseph Leonard Goldstein, Jaeil Han, Goncalo Vale, Jeffrey G. McDonald, Joachim Seemann, Joshua T. Mendell, Fei-Ran Lu;
Last step in the path of LDL cholesterol from lysosome to plasma membrane to ER is governed by phosphatidylserine.
Proc. Natl. Acad. Sci. U.S.A. 117:18521-18529(2020)

Cross-references
CRISP screens repositories BioGRID_ORCS_Cell_line; 1386
Encyclopedic resources Wikidata; Q123033576
Entry history
Entry creation05-Oct-2023
Last entry update10-Apr-2025
Version number4