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Cellosaurus Hi-5 Rix4446 (CVCL_RW20)

[Text version]
Cell line name Hi-5 Rix4446
Synonyms Hi-5 Rix 4446; Rix4446
Accession CVCL_RW20
Resource Identification Initiative To cite this cell line use: Hi-5 Rix4446 (RRID:CVCL_RW20)
Comments Group: Insect cell line.
Group: Recombinant protein production insect cell line.
Group: Vaccine production cell line.
Biotechnology: Used for the production of the papilloma vaccine Cervarix. The C-terminally truncated proteins L1 of HPV-16 and HPV-18 are separately produced in this cell line using a recombinant baculovirus expression system.
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Species of origin Trichoplusia ni (Cabbage looper) (NCBI Taxonomy: 7111)
Hierarchy Parent: CVCL_C190 (BTI-Tn-5B1-4)
Sex of cell Sex unspecified
Age at sampling Embryonic stage
Category Spontaneously immortalized cell line

PubMed=22265860; DOI=10.1016/j.vaccine.2012.01.016
Cox M.M.J.
Recombinant protein vaccines produced in insect cells.
Vaccine 30:1759-1766(2012)

Cell line databases/resources ICLDB; hi-5-rix4446
Encyclopedic resources Wikidata; Q54889518
Entry history
Entry creation05-Mar-2018
Last entry update29-Jun-2023
Version number8