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Cellosaurus BT048 (CVCL_RU29)

[Text version]
Cell line name BT048
Synonyms BT48; BT-48
Accession CVCL_RU29
Resource Identification Initiative To cite this cell line use: BT048 (RRID:CVCL_RU29)
Comments Group: Cancer stem cell line.
Omics: Transcriptome analysis by microarray.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=26095605).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 68Y
Category Cancer cell line
Publications

PubMed=19544433; DOI=10.1002/stem.98
Kelly J.J.P., Stechishin O.D.M., Chojnacki A., Lun X.-Q., Sun B.-C., Senger D.L., Forsyth P., Auer R.N., Dunn J.F., Cairncross J.G., Parney I.F., Weiss S.
Proliferation of human glioblastoma stem cells occurs independently of exogenous mitogens.
Stem Cells 27:1722-1733(2009)

PubMed=20388696; DOI=10.1093/neuonc/noq031
Kelly J.J.P., Blough M.D., Stechishin O.D.M., Chan J.A.W., Beauchamp D.C., Perizzolo M., Demetrick D.J., Steele L., Auer R.N., Hader W.J., Westgate M.R., Parney I.F., Jenkins R.B., Cairncross J.G., Weiss S.
Oligodendroglioma cell lines containing t(1;19)(q10;p10).
Neuro-oncol. 12:745-755(2010)

PubMed=20593219; DOI=10.1007/s11060-010-0283-9
Blough M.D., Beauchamp D.C., Westgate M.R., Kelly J.J.P., Cairncross J.G.
Effect of aberrant p53 function on temozolomide sensitivity of glioma cell lines and brain tumor initiating cells from glioblastoma.
J. Neurooncol. 102:1-7(2011)

PubMed=26095605; DOI=10.1016/j.stemcr.2015.05.010
Cusulin C., Chesnelong C., Bose P., Bilenky M., Kopciuk K., Chan J.A.W., Cairncross J.G., Jones S.J.M., Marra M.A., Luchman H.A., Weiss S.
Precursor states of brain tumor initiating cell lines are predictive of survival in xenografts and associated with glioblastoma subtypes.
Stem Cell Reports 5:1-9(2015)

PubMed=26245525; DOI=10.1093/neuonc/nov143
Davis B., Shen Y.-Q., Poon C.C., Luchman H.A., Stechishin O.D.M., Pontifex C.S., Wu W., Kelly J.J.P., Blough M.D.
Comparative genomic and genetic analysis of glioblastoma-derived brain tumor-initiating cells and their parent tumors.
Neuro-oncol. 18:350-360(2016)

Cross-references
Encyclopedic resources Wikidata; Q54798481
Gene expression databases GEO; GSM2155021
GEO; GSM2155024
Entry history
Entry creation05-Mar-2018
Last entry update29-Jun-2023
Version number8