ID   BT048
AC   CVCL_RU29
SY   BT48; BT-48
DR   GEO; GSM2155021
DR   GEO; GSM2155024
DR   Wikidata; Q54798481
RX   PubMed=19544433;
RX   PubMed=20388696;
RX   PubMed=20593219;
RX   PubMed=26095605;
RX   PubMed=26245525;
CC   Group: Cancer stem cell line.
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=26095605).
CC   Omics: Transcriptomics; Microarray.
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Brain; UBERON=UBERON_0000955.
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   68Y
CA   Cancer cell line
DT   Created: 05-03-18; Last updated: 10-04-25; Version: 10
//
RX   PubMed=26095605; DOI=10.1016/j.stemcr.2015.05.010; PMCID=PMC4618251;
RA   Cusulin, Carlo
RA   Chesnelong, Charles
RA   Bose, Pinaki
RA   Bilenky, Misha
RA   Kopciuk, Karen
RA   Chan, Jennifer Ai-Wen
RA   Cairncross, J. Gregory
RA   Jones, Steven J.M.
RA   Marra, Marco Antonio
RA   Luchman, Hema Artee
RA   Weiss, Samuel
RT   "Precursor states of brain tumor initiating cell lines are predictive
RT   of survival in xenografts and associated with glioblastoma
RT   subtypes.";
RL   Stem Cell Reports 5:1-9(2015).
//
RX   PubMed=20388696; DOI=10.1093/neuonc/noq031; PMCID=PMC2940664;
RA   Kelly, John J.P.
RA   Blough, Michael D.
RA   Stechishin, Owen D.M.
RA   Chan, Jennifer Ai-Wen
RA   Beauchamp, Desiree C.
RA   Perizzolo, Marco
RA   Demetrick, Douglas J.
RA   Steele, Lisa
RA   Auer, Roland N.
RA   Hader, Walter J.
RA   Westgate, Morgan R.
RA   Parney, Ian Frederick
RA   Jenkins, Robert Brian
RA   Cairncross, J. Gregory
RA   Weiss, Samuel
RT   "Oligodendroglioma cell lines containing t(1;19)(q10;p10).";
RL   Neuro-oncol. 12:745-755(2010).
//
RX   PubMed=26245525; DOI=10.1093/neuonc/nov143; PMCID=PMC4767234;
RA   Davis, Brad
RA   Shen, Yao-Qing
RA   Poon, Candice C.
RA   Luchman, Hema Artee
RA   Stechishin, Owen D.M.
RA   Pontifex, Carly Sabine
RA   Wu, Wei
RA   Kelly, John J.P.
RA   Blough, Michael D.
RG   Terry Fox Research Institute Glioblastoma Consortium;
RT   "Comparative genomic and genetic analysis of glioblastoma-derived
RT   brain tumor-initiating cells and their parent tumors.";
RL   Neuro-oncol. 18:350-360(2016).
//
RX   PubMed=19544433; DOI=10.1002/stem.98;
RA   Kelly, John J.P.
RA   Stechishin, Owen D.M.
RA   Chojnacki, Andrew
RA   Lun, Xue-Qing
RA   Sun, Bei-Chen
RA   Senger, Donna L.
RA   Forsyth, Peter
RA   Auer, Roland N.
RA   Dunn, Jeff F.
RA   Cairncross, J. Gregory
RA   Parney, Ian Frederick
RA   Weiss, Samuel
RT   "Proliferation of human glioblastoma stem cells occurs independently
RT   of exogenous mitogens.";
RL   Stem Cells 27:1722-1733(2009).
//
RX   PubMed=20593219; DOI=10.1007/s11060-010-0283-9;
RA   Blough, Michael D.
RA   Beauchamp, Desiree C.
RA   Westgate, Morgan R.
RA   Kelly, John J.P.
RA   Cairncross, J. Gregory
RT   "Effect of aberrant p53 function on temozolomide sensitivity of glioma
RT   cell lines and brain tumor initiating cells from glioblastoma.";
RL   J. Neurooncol. 102:1-7(2011).
//