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Cellosaurus BT012 (CVCL_RU28)

[Text version]
Cell line name BT012
Synonyms BT12; BT-12
Accession CVCL_RU28
Resource Identification Initiative To cite this cell line use: BT012 (RRID:CVCL_RU28)
Comments Group: Cancer stem cell line.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 59Y
Category Cancer cell line
Publications

PubMed=19544433; DOI=10.1002/stem.98
John J.P. Kelly, Owen D.M. Stechishin, Andrew Chojnacki, Xue-Qing Lun, Bei-Chen Sun, Donna L. Senger, Peter Forsyth, Roland N. Auer, Jeff F. Dunn, J. Gregory Cairncross, Ian Frederick Parney, Samuel Weiss;
Proliferation of human glioblastoma stem cells occurs independently of exogenous mitogens.
Stem Cells 27:1722-1733(2009)

PubMed=20388696; DOI=10.1093/neuonc/noq031; PMCID=PMC2940664
John J.P. Kelly, Michael D. Blough, Owen D.M. Stechishin, Jennifer Ai-Wen Chan, Desiree C. Beauchamp, Marco Perizzolo, Douglas J. Demetrick, Lisa Steele, Roland N. Auer, Walter J. Hader, Morgan R. Westgate ...Show all 15 authors... , Ian Frederick Parney, Robert Brian Jenkins, J. Gregory Cairncross, Samuel Weiss; Show fewer authors
Oligodendroglioma cell lines containing t(1;19)(q10;p10).
Neuro-oncol. 12:745-755(2010)

PubMed=20593219; DOI=10.1007/s11060-010-0283-9
Michael D. Blough, Desiree C. Beauchamp, Morgan R. Westgate, John J.P. Kelly, J. Gregory Cairncross;
Effect of aberrant p53 function on temozolomide sensitivity of glioma cell lines and brain tumor initiating cells from glioblastoma.
J. Neurooncol. 102:1-7(2011)

PubMed=26095605; DOI=10.1016/j.stemcr.2015.05.010; PMCID=PMC4618251
Carlo Cusulin, Charles Chesnelong, Pinaki Bose, Misha Bilenky, Karen Kopciuk, Jennifer Ai-Wen Chan, J. Gregory Cairncross, Steven J.M. Jones, Marco Antonio Marra, Hema Artee Luchman, Samuel Weiss;
Precursor states of brain tumor initiating cell lines are predictive of survival in xenografts and associated with glioblastoma subtypes.
Stem Cell Reports 5:1-9(2015)

PubMed=27006494; DOI=10.1158/1078-0432.CCR-15-1798
Xue-Qing Lun, J. Connor Wells, Natalie Grinshtein, Jennifer C. King, Xiao-Guang Hao, Ngoc-Ha Dang, Xiu-Ling Wang, Ahmed Aman, David Uehling, Alessandro Datti, Jeffrey L. Wrana ...Show all 18 authors... , Jacob C. Easaw, Hema Artee Luchman, Samuel Weiss, J. Gregory Cairncross, David Ross Kaplan, Stephen M. Robbins, Donna L. Senger; Show fewer authors
Disulfiram when combined with copper enhances the therapeutic effects of temozolomide for the treatment of glioblastoma.
Clin. Cancer Res. 22:3860-3875(2016)

Cross-references
Encyclopedic resources Wikidata; Q54798479
Gene expression databases GEO; GSM2155019
GEO; GSM2155022
Entry history
Entry creation05-Mar-2018
Last entry update10-Apr-2025
Version number7