Cellosaurus logo
expasy logo

Cellosaurus MEL2 (CVCL_RU21)

[Text][XML][JSON]
Cell line name MEL2
Synonyms MEL-2; PureStem MEL2, NCr-fac progenitor; ACTC268
Accession CVCL_RU21
Resource Identification Initiative To cite this cell line use: MEL2 (RRID:CVCL_RU21)
Comments Group: Patented cell line.
From: ESI BIO - BioTime, Inc. (ES Cell International); Alameda; USA.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); PTA-11150.
Characteristics: Undergoes chondrogenesis in a progenitor with markers of head and limb mesenchyme and low levels of hypertrophic marker COL10A1.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9773 (WA09)
Sex of cell Female
Age at sampling Blastocyst stage
Category Somatic stem cell
Web pages Provider; ESI BIO; ES-268; https://web.archive.org/web/20141202113834/http://www.esibio.com/purestemr-mel2-ncr-fac-progenitor/
Publications

PubMed=18462054; DOI=10.2217/17460751.3.3.287
Michael D. West, R. Geoffrey Sargent, Jeff Long, Colleen Brown, Jing-Song Chu, Steven Kessler, Nikita Derugin, Janani Sampathkumar, Courtney Burrows, Homayoun Vaziri, Roy Williams ...Show all 15 authors... , Karen B. Chapman, David Larocca, Jeanne Frances Loring, James T. Murai; Show fewer authors
The ACTCellerate initiative: large-scale combinatorial cloning of novel human embryonic stem cell derivatives.
Regen. Med. 3:287-308(2008)

Patent=US8685386
Michael D. West, Hal Sternberg, Karen B. Chapman;
Methods and compositions for in vitro and in vivo chondrogenesis.
Patent number US8685386, 01-Apr-2014

Cross-references
Encyclopedic resources Wikidata; Q54905154
Entry history
Entry creation05-Mar-2018
Last entry update10-Apr-2025
Version number7