Cellosaurus logo
expasy logo

Cellosaurus MEL2 (CVCL_RU21)

[Text version]
Cell line name MEL2
Synonyms MEL-2; PureStem MEL2, NCr-fac progenitor; ACTC268
Accession CVCL_RU21
Resource Identification Initiative To cite this cell line use: MEL2 (RRID:CVCL_RU21)
Comments Group: Patented cell line.
From: ESI BIO - BioTime, Inc. (ES Cell International); Alameda; USA.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); PTA-11150.
Characteristics: Undergoes chondrogenesis in a progenitor with markers of head and limb mesenchyme and low levels of hypertrophic marker COL10A1.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9773 (WA09)
Sex of cell Female
Age at sampling Blastocyst stage
Category Somatic stem cell
Web pages http://www.esibio.com/purestemr-mel2-ncr-fac-progenitor/
Publications

PubMed=18462054; DOI=10.2217/17460751.3.3.287
West M.D., Sargent R.G., Long J., Brown C., Chu J.-S., Kessler S., Derugin N., Sampathkumar J., Burrows C., Vaziri H., Williams R., Chapman K.B., Larocca D., Loring J.F., Murai J.T.
The ACTCellerate initiative: large-scale combinatorial cloning of novel human embryonic stem cell derivatives.
Regen. Med. 3:287-308(2008)

Patent=US8685386
West M.D., Sternberg H., Chapman K.B.
Methods and compositions for in vitro and in vivo chondrogenesis.
Patent number US8685386, 01-Apr-2014

Cross-references
Encyclopedic resources Wikidata; Q54905154
Entry history
Entry creation05-Mar-2018
Last entry update29-Jun-2023
Version number6