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Cellosaurus Tn-NVN (CVCL_RT22)

[Text version]
Cell line name Tn-NVN
Accession CVCL_RT22
Resource Identification Initiative To cite this cell line use: Tn-NVN (RRID:CVCL_RT22)
Comments Group: Insect cell line.
Group: Patented cell line.
Group: Recombinant protein production insect cell line.
Virology: Cured of TnCLV infection by ribavirin-treatment.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Species of origin Trichoplusia ni (Cabbage looper) (NCBI Taxonomy: 7111)
Hierarchy Parent: CVCL_C412 (TN-368)
Sex of cell Female
Age at sampling Adult stage
Category Spontaneously immortalized cell line
Publications

PubMed=29133148; DOI=10.1016/j.pep.2017.11.002; PMCID=PMC5826799
Christoph Geisler, Donald L. Jarvis;
Adventitious viruses in insect cell lines used for recombinant protein expression.
Protein Expr. Purif. 144:25-32(2018)

PubMed=32662870; DOI=10.1002/bit.27494; PMCID=PMC8007066
Ajay B. Maghodia, Christoph Geisler, Donald L. Jarvis;
A new nodavirus-negative Trichoplusia ni cell line for baculovirus-mediated protein production.
Biotechnol. Bioeng. 117:3248-3264(2020)

Patent=US11473055
Ajay B. Maghodia, Christoph Geisler, Donald L. Jarvis;
Virus-free cell lines and methods for obtaining same.
Patent number US11473055, 18-Oct-2022

Cross-references
Cell line databases/resources ICLDB; tn-nvn
Encyclopedic resources Wikidata; Q54972720
Entry history
Entry creation05-Mar-2018
Last entry update19-Dec-2024
Version number11