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Cellosaurus TN-368 (CVCL_C412)

[Text version]
Cell line name TN-368
Synonyms Tn-368; Tn 368; TN368; Tn368; Trichoplusia ni 368
Accession CVCL_C412
Resource Identification Initiative To cite this cell line use: TN-368 (RRID:CVCL_C412)
Comments Group: Insect cell line.
Group: Recombinant protein production insect cell line.
Virology: Infected with alphanodavirus TnCLV (PubMed=29133148).
Doubling time: 14.5 hours (PubMed=669727); ~24 hours (DSMZ=ACC-177).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Species of origin Trichoplusia ni (Cabbage looper) (NCBI Taxonomy: 7111)
Hierarchy Children:
CVCL_Z078 (TN-368-10)CVCL_Z079 (TN-368-13)CVCL_C2R8 (TN-368-3)
CVCL_C2R9 (TN-368-5)CVCL_C2RA (TN-368-8)CVCL_C413 (TN-368A)
Sex of cell Female
Age at sampling Adult stage
Category Spontaneously immortalized cell line

PubMed=16057320; DOI=10.1038/226466b0
Hink W.F.
Established insect cell line from the cabbage looper, Trichoplusia ni.
Nature 226:466-467(1970)

PubMed=4471170; DOI=10.1007/BF02615331
McIntosh A.H., Rechtoris C.
Insect cells: colony formation and cloning in agar medium.
In Vitro 10:1-5(1974)

PubMed=1104895; DOI=10.1128/JVI.16.6.1630-1637.1975
Volkman L.E., Summers M.D.
Nuclear polyhedrosis virus detection: relative capabilities of clones developed from Trichoplusia ni ovarian cell line TN-368 to serve as indicator cells in a plaque assay.
J. Virol. 16:1630-1637(1975)

Volkman L.E., Summers M.D.
Comparative studies with clones derived from a cabbage looper ovarian cell line, TN-368.
(In) Invertebrate tissue culture: applications in medicine, biology and agriculture; Kurstak E., Maramorosch K. (eds.); pp.289-296; Academic Press; New York (1976)

Hink W.F., Strauss E.
Growth of the Trichoplusia ni (TN-368) cell line in suspension culture.
(In) Invertebrate tissue culture: applications in medicine, biology and agriculture; Kurstak E., Maramorosch K. (eds.); pp.297-300; Academic Press; New York (1976)

PubMed=1017845; DOI=10.1007/BF02797470
Rechtoris C., McIntosh A.H.
A cytotoxic substance in insect cell culture spent media.
In Vitro 12:678-681(1976)

PubMed=669727; DOI=10.1007/BF02618228
Lynn D.E., Hink W.F.
Cell cycle analysis and synchronization of the TN-368 insect cell line.
In Vitro 14:236-238(1978)

Herrera R.J.
Cytological, cytogenetic and biochemical studies on several permanent insect cell lines.
Thesis PhD (1982), Fordham University, United States

PubMed=16346059; DOI=10.1128/AEM.44.1.227-233.1982
Volkman L.E., Goldsmith P.A.
Generalized immunoassay for Autographa californica nuclear polyhedrosis virus infectivity in vitro.
Appl. Environ. Microbiol. 44:227-233(1982)

Bilimoria S.L., Carpenter W.M.
TN-368A: an attached strain of Hink's Trichoplusia ni (TN-368) cell line.
In Vitro 19:870-874(1983)

Koval T.M.
Radiosensitivity of cultured insect cells: I. Lepidoptera.
Radiat. Res. 96:118-126(1983)

PubMed=16593348; DOI=10.1073/pnas.80.15.4752
Koval T.M.
Intrinsic resistance to the lethal effects of X-irradiation in insect and arachnid cells.
Proc. Natl. Acad. Sci. U.S.A. 80:4752-4755(1983)

Harvey G.T., Sohi S.S.
Isozyme characterization of 28 cell lines from five insect species.
Can. J. Zool. 63:2270-2276(1985)

Harvey G.T., Sohi S.S.
Isozyme characterization of 8 hymenopteran and 20 lepidopteran cell lines.
(In) Invertebrate cell system applications, Vol. I; Mitsuhashi J. (eds.); pp.71-75; CRC Press; Boca Raton (1989)

PubMed=1367489; DOI=10.1021/bp00007a002
Hink W.F., Thomsen D.R., Davidson D.J., Meyer A.L., Castellino F.J.
Expression of three recombinant proteins using baculovirus vectors in 23 insect cell lines.
Biotechnol. Prog. 7:9-14(1991)

PubMed=1369220; DOI=10.1021/bp00017a003
Wickham T.J., Davis T., Granados R.R., Shuler M.L., Wood H.A.
Screening of insect cell lines for the production of recombinant proteins and infectious virus in the baculovirus expression system.
Biotechnol. Prog. 8:391-396(1992)

PubMed=1561320; DOI=10.2307/357848
Styer S.C., Griffiths T.D.
Effect of UVC light on growth, incorporation of thymidine, and DNA chain elongation in cells derived from the Indian meal moth and the cabbage looper.
Radiat. Res. 130:72-78(1992)

PubMed=8314732; DOI=10.1007/BF02633986
Davis T.R., Wickham T.J., McKenna K.A., Granados R.R., Shuler M.L., Wood H.A.
Comparative recombinant protein production of eight insect cell lines.
In Vitro Cell. Dev. Biol. Anim. 29:388-390(1993)

PubMed=12623313; DOI=10.1016/S0022-2011(03)00002-8
Lynn D.E.
Comparative susceptibilities of twelve insect cell lines to infection by three baculoviruses.
J. Invertebr. Pathol. 82:129-131(2003)

PubMed=15926859; DOI=10.1290/0412081.1
Chen Y.P., Gundersen-Rindal D.E., Lynn D.E.
Baculovirus-based expression of an insect viral protein in 12 different insect cell lines.
In Vitro Cell. Dev. Biol. Anim. 41:43-49(2005)

PubMed=29133148; DOI=10.1016/j.pep.2017.11.002
Geisler C., Jarvis D.L.
Adventitious viruses in insect cell lines used for recombinant protein expression.
Protein Expr. Purif. 144:25-32(2017)

Cell line collections (Providers) DSMZ; ACC-177
Cell line databases/resources CLO; CLO_0009377
CLDB; cl4534
DSMZCellDive; ACC-177
ICLDB; tn-368
Encyclopedic resources Wikidata; Q54972712
Entry history
Entry creation22-Oct-2012
Last entry update29-Jun-2023
Version number16