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Cellosaurus TN-368 (CVCL_C412)

[Text version]
Cell line name TN-368
Synonyms Tn-368; Tn 368; TN368; Tn368; Trichoplusia ni 368; Tni
Accession CVCL_C412
Resource Identification Initiative To cite this cell line use: TN-368 (RRID:CVCL_C412)
Comments Group: Insect cell line.
Group: Recombinant protein production insect cell line.
Virology: Infected with alphanodavirus TnCLV (PubMed=29133148).
Doubling time: 14.5 hours (PubMed=669727); ~24 hours (DSMZ=ACC-177).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Species of origin Trichoplusia ni (Cabbage looper) (NCBI Taxonomy: 7111)
Hierarchy Children:
CVCL_Z078 (TN-368-10)CVCL_Z079 (TN-368-13)CVCL_C2R8 (TN-368-3)
CVCL_C2R9 (TN-368-5)CVCL_C2RA (TN-368-8)CVCL_C413 (TN-368A)
CVCL_Z257 (TN-CL1)CVCL_RT22 (Tn-NVN)
Sex of cell Female
Age at sampling Adult stage
Category Spontaneously immortalized cell line
Publications

PubMed=16057320; DOI=10.1038/226466b0
Walter Frederic Hink;
Established insect cell line from the cabbage looper, Trichoplusia ni.
Nature 226:466-467(1970)

DOI=10.1016/B978-0-12-709902-6.50017-0
Walter Frederic Hink;
A catalog of invertebrate cell lines.
(In book chapter) Invertebrate tissue culture, Vol. II; Vago, Constantin (eds.); pp.363-387; Academic Press; New York; USA (1972)

PubMed=4471170; DOI=10.1007/BF02615331
Arthur H. McIntosh, Carol Rechtoris;
Insect cells: colony formation and cloning in agar medium.
In Vitro 10:1-5(1974)

PubMed=1104895; DOI=10.1128/JVI.16.6.1630-1637.1975; PMCID=PMC355772
Loy E. Volkman, Max Duane Summers;
Nuclear polyhedrosis virus detection: relative capabilities of clones developed from Trichoplusia ni ovarian cell line TN-368 to serve as indicator cells in a plaque assay.
J. Virol. 16:1630-1637(1975)

DOI=10.1016/B978-0-12-429740-1.50032-1
Loy E. Volkman, Max Duane Summers;
Comparative studies with clones derived from a cabbage looper ovarian cell line, TN-368.
(In book chapter) Invertebrate tissue culture: applications in medicine, biology and agriculture; Kurstak, Edouard & Maramorosch, Karl (eds.); pp.289-296; Academic Press; New York; USA (1976)

DOI=10.1016/B978-0-12-429740-1.50033-3
Walter Frederic Hink, Ethan Strauss;
Growth of the Trichoplusia ni (TN-368) cell line in suspension culture.
(In book chapter) Invertebrate tissue culture: applications in medicine, biology and agriculture; Kurstak, Edouard & Maramorosch, Karl (eds.); pp.297-300; Academic Press; New York; USA (1976)

PubMed=1017845; DOI=10.1007/BF02797470
Carol Rechtoris, Arthur H. McIntosh;
A cytotoxic substance in insect cell culture spent media.
In Vitro 12:678-681(1976)

PubMed=669727; DOI=10.1007/BF02618228
Dwight E. Lynn, Walter Frederic Hink;
Cell cycle analysis and synchronization of the TN-368 insect cell line.
In Vitro 14:236-238(1978)

CLPUB00466
Rene J. Herrera;
Cytological, cytogenetic and biochemical studies on several permanent insect cell lines.
Thesis PhD (1982); Fordham University; New York; USA

PubMed=16346059; DOI=10.1128/AEM.44.1.227-233.1982; PMCID=PMC241993
Loy E. Volkman, Phyllis A. Goldsmith;
Generalized immunoassay for Autographa californica nuclear polyhedrosis virus infectivity in vitro.
Appl. Environ. Microbiol. 44:227-233(1982)

DOI=10.1007/BF02618167
Shan L. Bilimoria, W.M. Carpenter;
TN-368A: an attached strain of Hink's Trichoplusia ni (TN-368) cell line.
In Vitro 19:870-874(1983)

DOI=10.2307/3576171
Thomas M. Koval;
Radiosensitivity of cultured insect cells: I. Lepidoptera.
Radiat. Res. 96:118-126(1983)

PubMed=16593348; DOI=10.1073/pnas.80.15.4752; PMCID=PMC384122
Thomas M. Koval;
Intrinsic resistance to the lethal effects of X-irradiation in insect and arachnid cells.
Proc. Natl. Acad. Sci. U.S.A. 80:4752-4755(1983)

DOI=10.1139/z85-337
George Thomas Harvey, Sardar S. Sohi;
Isozyme characterization of 28 cell lines from five insect species.
Can. J. Zool. 63:2270-2276(1985)

CLPUB00491
George Thomas Harvey, Sardar S. Sohi;
Isozyme characterization of 8 hymenopteran and 20 lepidopteran cell lines.
(In book chapter) Invertebrate cell system applications, Vol. I; Mitsuhashi, Jun (eds.); pp.71-75; CRC Press; Boca Raton; USA (1989)

PubMed=1367489; DOI=10.1021/bp00007a002
Walter Frederic Hink, Darrell R. Thomsen, Don J. Davidson, Annette L. Meyer, Francis J. Castellino;
Expression of three recombinant proteins using baculovirus vectors in 23 insect cell lines.
Biotechnol. Prog. 7:9-14(1991)

PubMed=1369220; DOI=10.1021/bp00017a003
Thomas J. Wickham, Thomas R. Davis, Robert R. Granados, Michael Louis Shuler, H. Alan Wood;
Screening of insect cell lines for the production of recombinant proteins and infectious virus in the baculovirus expression system.
Biotechnol. Prog. 8:391-396(1992)

PubMed=1561320; DOI=10.2307/357848
Susan C. Styer, Thomas Daniel Griffiths;
Effect of UVC light on growth, incorporation of thymidine, and DNA chain elongation in cells derived from the Indian meal moth and the cabbage looper.
Radiat. Res. 130:72-78(1992)

PubMed=8314732; DOI=10.1007/BF02633986
Thomas R. Davis, Thomas J. Wickham, Kevin A. McKenna, Robert R. Granados, Michael Louis Shuler, H. Alan Wood;
Comparative recombinant protein production of eight insect cell lines.
In Vitro Cell. Dev. Biol. Anim. 29:388-390(1993)

PubMed=12623313; DOI=10.1016/S0022-2011(03)00002-8
Dwight E. Lynn;
Comparative susceptibilities of twelve insect cell lines to infection by three baculoviruses.
J. Invertebr. Pathol. 82:129-131(2003)

PubMed=15926859; DOI=10.1290/0412081.1
Yan-Ping Chen, Dawn E. Gundersen-Rindal, Dwight E. Lynn;
Baculovirus-based expression of an insect viral protein in 12 different insect cell lines.
In Vitro Cell. Dev. Biol. Anim. 41:43-49(2005)

PubMed=29133148; DOI=10.1016/j.pep.2017.11.002; PMCID=PMC5826799
Christoph Geisler, Donald L. Jarvis;
Adventitious viruses in insect cell lines used for recombinant protein expression.
Protein Expr. Purif. 144:25-32(2018)

Cross-references
Cell line collections (Providers) DSMZ; ACC-177
Cell line databases/resources CLO; CLO_0009377
CLDB; cl4534
DSMZCellDive; ACC-177
ICLDB; tn-368
Encyclopedic resources Wikidata; Q54972712
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number18