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Cellosaurus IGR-1rDACARB40 (CVCL_RS52)

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Cell line name IGR-1rDACARB40
Accession CVCL_RS52
Resource Identification Initiative To cite this cell line use: IGR-1rDACARB40 (RRID:CVCL_RS52)
Comments Part of: Resistant Cancer Cell Line (RCCL) collection.
Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_4305; Dacarbazine (DTIC; (5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide)).
Derived from site: Metastatic; Inguinal lymph node; UBERON=UBERON_0001542.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Lys (c.1798_1799delGTinsAA); ClinVar=VCV000375941; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9801; RAC1; Simple; p.Pro29Ser (c.85C>T); ClinVar=VCV000376362; Zygosity=Heterozygous (from parent cell line).
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1303 (IGR-1)
Sex of cell Male
Age at sampling 42Y
Category Cancer cell line
Web pages Provider; RCCL; -; https://www.wass-michaelislab.org/rccl.php
Cross-references
Cell line databases/resources cancercelllines; CVCL_RS52
Encyclopedic resources Wikidata; Q54897360
Entry history
Entry creation05-Mar-2018
Last entry update10-Apr-2025
Version number13