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Cellosaurus UKF-NB-3rRITA10muM (CVCL_RS21)

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Cell line name UKF-NB-3rRITA10muM
Accession CVCL_RS21
Resource Identification Initiative To cite this cell line use: UKF-NB-3rRITA10muM (RRID:CVCL_RS21)
Comments Part of: Resistant Cancer Cell Line (RCCL) collection.
Selected for resistance to: ChEBI; CHEBI_94980; [5-[5-[5-(hydroxymethyl)-2-thiophenyl]-2-furanyl]-2-thiophenyl]methanol (RITA).
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9904 (UKF-NB-3)
Sex of cell Female
Category Cancer cell line
Web pages Provider; RCCL; -; https://www.wass-michaelislab.org/rccl.php
Publications

PubMed=22476102; DOI=10.1038/cddis.2012.35; PMCID=PMC3358013
Martin Michaelis, Florian Rothweiler, Bishr Agha, Susanne Barth, Yvonne Voges, Nadine Loschmann, Andreas von Deimling, Rainer Breitling, Hans-Wilhelm Doerr, Franz Rodel, Daniel Speidel, Jindrich Cinatl Jr.;
Human neuroblastoma cells with acquired resistance to the p53 activator RITA retain functional p53 and sensitivity to other p53 activating agents.
Cell Death Dis. 3:e294.1-e294.8(2012)

Cross-references
Encyclopedic resources Wikidata; Q54990354
Entry history
Entry creation05-Mar-2018
Last entry update10-Apr-2025
Version number9