Cellosaurus logo
expasy logo

Cellosaurus NLFrMEL3000 (CVCL_RR49)

[Text version]
Cell line name NLFrMEL3000
Accession CVCL_RR49
Resource Identification Initiative To cite this cell line use: NLFrMEL3000 (RRID:CVCL_RR49)
Comments Part of: Resistant Cancer Cell Line (RCCL) collection.
Selected for resistance to: ChEBI; CHEBI:28876; Melphalan (L-phenylalanine mustard; LPAM; Alkeran).
Sequence variations
  • Mutation; HGNC; 8975; PIK3CA; Simple; p.Arg524Met (c.1571G>T); Zygosity=Heterozygous (from parent cell line).
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_E217 (NLF)
Sex of cell Male
Age at sampling 3Y
Category Cancer cell line
Web pages https://www.wass-michaelislab.org/rccl.php
Publications

PubMed=24466371; DOI=10.1593/tlo.13544
Loschmann N., Michaelis M., Rothweiler F., Zehner R., Cinatl J., Voges Y., Sharifi M., Riecken K., Meyer J., von Deimling A., Fichtner I., Ghafourian T., Westermann F., Cinatl J. Jr.
Testing of SNS-032 in a panel of human neuroblastoma cell lines with acquired resistance to a broad range of drugs.
Transl. Oncol. 6:685-696(2013)

Cross-references
Encyclopedic resources Wikidata; Q54930701
Entry history
Entry creation05-Mar-2018
Last entry update21-Mar-2023
Version number6