Cellosaurus logo
expasy logo

Cellosaurus UKF-NB-3rDACARB8 (CVCL_RQ61)

[Text version]
Cell line name UKF-NB-3rDACARB8
Synonyms UKF-NB-3rDAC8
Accession CVCL_RQ61
Resource Identification Initiative To cite this cell line use: UKF-NB-3rDACARB8 (RRID:CVCL_RQ61)
Comments Part of: Resistant Cancer Cell Line (RCCL) collection.
Selected for resistance to: ChEBI; CHEBI_4305; Dacarbazine (DTIC; (5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide)).
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9904 (UKF-NB-3)
Sex of cell Female
Category Cancer cell line
Web pages Provider; RCCL; -; https://www.wass-michaelislab.org/rccl.php
Publications

PubMed=22170099; DOI=10.1038/cddis.2011.129; PMCID=PMC3252738
Martin Michaelis, Florian Rothweiler, Susanne Barth, Jaroslaw Cinatl, Marijke van Rikxoort, Nadine Loschmann, Yvonne Voges, Rainer Breitling, Andreas von Deimling, Franz Rodel, Kristoffer Weber ...Show all 17 authors... , Boris Fehse, Elisabeth Mack, Thorsten Stiewe, Hans-Wilhelm Doerr, Daniel Speidel, Jindrich Cinatl Jr.; Show fewer authors
Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells.
Cell Death Dis. 2:e243.1-e243.8(2011)

Cross-references
Encyclopedic resources Wikidata; Q54990335
Entry history
Entry creation05-Mar-2018
Last entry update10-Apr-2025
Version number10