Cellosaurus cell line CU-ACC2 (CVCL

Cellosaurus CU-ACC2 (CVCL_RQ01)

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Cell line name

CU-ACC2

Synonyms

Colorado University-AdrenoCortical cancer 2

Accession

CVCL_RQ01

Resource Identification Initiative

To cite this cell line use: CU-ACC2 (RRID:CVCL_RQ01)

Comments

Doubling time: 29 hours (Note=At 10th passage) (PubMed=29371329).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.

Sequence variations

Mutation; HGNC; HGNC:7325; MSH2; Unexplicit; Ex1-6del; Zygosity=Unspecified (PubMed=29371329).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly245Ser (c.733G>A); ClinVar=VCV000012365; Zygosity=Unspecified (PubMed=29371329).

Disease

Adrenal cortex carcinoma (NCIt: C9325)
Lynch syndrome (NCIt: C8494)
Adrenocortical carcinoma (ORDO: Orphanet_1501)
Lynch syndrome (ORDO: Orphanet_144)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

26Y

Category

Cancer cell line

STR profile

Source(s): PubMed=29371329

Markers:

Amelogenin	X
CSF1PO	11,12
D3S1358	13,14
D5S818	11,12
D7S820	8
D8S1179	13,14
D13S317	13
D16S539	11,12
D18S51	19,20
D21S11	29
FGA	24
Penta D	14
Penta E	11
TH01	9.3
TPOX	8
vWA	16,18,20

Publications

PubMed=29371329; DOI=10.1530/ERC-17-0447; PMCID=PMC5831504
Katja Kiseljak-Vassiliades, Yu Zhang, Stacey M. Bagby, Adwitiya Kar, Nikita Pozdeyev, Mei Xu, Katherine Gowan, Vibha Sharma, Christopher D. Raeburn, Maria Belen Albuja-Cruz, Kenneth L. Jones ...Show all 17 authors... , Lauren Fishbein, Rebecca E. Schweppe, Hilary Somerset, Todd M. Pitts, Stephen Leong, Margaret E. Wierman; Show fewer authors
Development of new preclinical models to advance adrenocortical carcinoma research.
Endocr. Relat. Cancer 25:437-451(2018)

PubMed=35764904; DOI=10.1007/s12020-022-03112-w; PMCID=PMC9385758
Sandra Sigala, Elisa Rossini, Andrea Abate, Mariangela Tamburello, Stefan Richard Bornstein, Constanze Hantel;
An update on adrenocortical cell lines of human origin.
Endocrine 77:432-437(2022)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_RQ01

Encyclopedic resources

Wikidata; Q54814834

Entry history

Entry creation

05-Mar-2018

Last entry update

10-Apr-2025

Version number