ID   CU-ACC2
AC   CVCL_RQ01
SY   Colorado University-AdrenoCortical cancer 2
DR   cancercelllines; CVCL_RQ01
DR   Wikidata; Q54814834
RX   PubMed=29371329;
RX   PubMed=35764904;
CC   Doubling time: 29 hours (Note=At 10th passage) (PubMed=29371329).
CC   Sequence variation: Mutation; HGNC; HGNC:7325; MSH2; Unexplicit; Ex1-6del; Zygosity=Unspecified (PubMed=29371329).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly245Ser (c.733G>A); ClinVar=VCV000012365; Zygosity=Unspecified (PubMed=29371329).
CC   Omics: Genomics; Whole exome sequencing.
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
ST   Source(s): PubMed=29371329
ST   Amelogenin: X
ST   CSF1PO: 11,12
ST   D13S317: 13
ST   D16S539: 11,12
ST   D18S51: 19,20
ST   D21S11: 29
ST   D3S1358: 13,14
ST   D5S818: 11,12
ST   D7S820: 8
ST   D8S1179: 13,14
ST   FGA: 24
ST   Penta D: 14
ST   Penta E: 11
ST   TH01: 9.3
ST   TPOX: 8
ST   vWA: 16,18,20
DI   NCIt; C9325; Adrenal cortex carcinoma
DI   NCIt; C8494; Lynch syndrome
DI   ORDO; Orphanet_1501; Adrenocortical carcinoma
DI   ORDO; Orphanet_144; Lynch syndrome
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   26Y
CA   Cancer cell line
DT   Created: 05-03-18; Last updated: 10-04-25; Version: 12
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RX   PubMed=29371329; DOI=10.1530/ERC-17-0447; PMCID=PMC5831504;
RA   Kiseljak-Vassiliades K., Zhang Y., Bagby S.M., Kar A., Pozdeyev N.,
RA   Xu M., Gowan K., Sharma V., Raeburn C.D., Albuja-Cruz M.B., Jones K.L.,
RA   Fishbein L., Schweppe R.E., Somerset H., Pitts T.M., Leong S.,
RA   Wierman M.E.;
RT   "Development of new preclinical models to advance adrenocortical
RT   carcinoma research.";
RL   Endocr. Relat. Cancer 25:437-451(2018).
//
RX   PubMed=35764904; DOI=10.1007/s12020-022-03112-w; PMCID=PMC9385758;
RA   Sigala S., Rossini E., Abate A., Tamburello M., Bornstein S.R.,
RA   Hantel C.;
RT   "An update on adrenocortical cell lines of human origin.";
RL   Endocrine 77:432-437(2022).
//