| Cell line name |
A375P-5 |
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| Accession |
CVCL_RN37 |
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| Resource Identification Initiative |
To cite this cell line use: A375P-5 (RRID:CVCL_RN37) |
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| Comments |
Population: Caucasian.
Derived from site: In situ; Leg, skin; UBERON=UBERON_0001511. |
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| Sequence variations |
- Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Glu61Ter (c.181G>T) (p.Gly75Val, c.224G>T); ClinVar=VCV000376309; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Glu69Ter (c.205G>T) (p.Gly83Val, c.248G>T); ClinVar=VCV000376308; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
|
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| Disease |
Amelanotic melanoma (NCIt: C3802) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_6233 (A375-P) |
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| Sex of cell |
Female |
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| Age at sampling |
54Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=2731157; DOI=10.1016/0304-3835(89)90148-1
Karin H. Yohem, Elisabeth A. Seftor, Frank L. Meyskens Jr., Mary J.C. Hendrix;
Cloning efficiency of human melanoma cells is modulated after invasion through a reconstituted basement membrane.
Cancer Lett. 45:135-143(1989) |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_RN37
|
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| Encyclopedic resources |
Wikidata; Q54606871
|
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| Entry history |
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| Entry creation | 05-Mar-2018 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 14 |
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