Cellosaurus logo
expasy logo

Cellosaurus UKBi011-A-1 (CVCL_RM82)

[Text version]
Cell line name UKBi011-A-1
Synonyms APOE-KO; iLB-AD + ApoE KO
Accession CVCL_RM82
Resource Identification Initiative To cite this cell line use: UKBi011-A-1 (RRID:CVCL_RM82)
Comments From: Bioneer A/S; Horsholm; Denmark.
Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; 613; APOE.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Disease Alzheimer's disease (NCIt: C2866)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_LE34 (UKBi011-A)
Sex of cell Male
Age at sampling 80Y
Category Induced pluripotent stem cell

PubMed=33556820; DOI=10.1016/j.scr.2021.102180
Schmid B., Holst B., Clausen C., Bahnassawy L., Reinhardt P., Bakker M.H.M., Diaz-Guerra E., Vicario-Abejon C., Martino-Adami P.V., Thoenes M., Ramirez A., Fliessbach K., Grezella C., Brustle O., Peitz M., Ebneth A., Cabrera-Socorro A.
Generation of a set of isogenic iPSC lines carrying all APOE genetic variants (E2/E3/E4) and knock-out for the study of APOE biology in health and disease.
Stem Cell Res. 52:102180-102180(2021)

Cell line collections (Providers) EBiSC; UKBi011-A-1
ECACC; 66540617 - Discontinued
Cell line databases/resources hPSCreg; UKBi011-A-1
Biological sample resources BioSamples; SAMEA104243174
Encyclopedic resources Wikidata; Q54990269
Entry history
Entry creation05-Mar-2018
Last entry update30-Jan-2024
Version number7