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Cellosaurus UKBi011-A-1 (CVCL_RM82)

[Text version]
Cell line name UKBi011-A-1
Synonyms APOE-KO; iLB-AD + ApoE KO
Accession CVCL_RM82
Resource Identification Initiative To cite this cell line use: UKBi011-A-1 (RRID:CVCL_RM82)
Comments From: Bioneer A/S; Horsholm; Denmark.
Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:613; APOE.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Disease Alzheimer's disease (NCIt: C2866)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_LE34 (UKBi011-A)
Sex of cell Male
Age at sampling 80Y
Category Induced pluripotent stem cell
Publications

PubMed=33556820; DOI=10.1016/j.scr.2021.102180
Benjamin Schmid, Bjorn Holst, Christian Clausen, Lamiaa Bahnassawy, Peter Reinhardt, Margot H.M. Bakker, Eva Diaz-Guerra, Carlos Vicario-Abejon, Pamela V. Martino-Adami, Michaela Thoenes, Alfredo Ramirez ...Show all 17 authors... , Klaus Fliessbach, Clara Grezella, Oliver Brustle, Michael Peitz, Andreas Ebneth, Alfredo Cabrera-Socorro; Show fewer authors
Generation of a set of isogenic iPSC lines carrying all APOE genetic variants (E2/E3/E4) and knock-out for the study of APOE biology in health and disease.
Stem Cell Res. 52:102180-102180(2021)

Cross-references
Cell line collections (Providers) EBiSC; UKBi011-A-1
ECACC; 66540617 - Discontinued
Cell line databases/resources hPSCreg; UKBi011-A-1
Biological sample resources BioSamples; SAMEA104243174
Encyclopedic resources Wikidata; Q54990269
Entry history
Entry creation05-Mar-2018
Last entry update19-Dec-2024
Version number8