Cellosaurus logo
expasy logo

Cellosaurus UKBi011-A (CVCL_LE34)

[Text version]
Cell line name UKBi011-A
Synonyms iLB-AD-169bm-S24
Accession CVCL_LE34
Resource Identification Initiative To cite this cell line use: UKBi011-A (RRID:CVCL_LE34)
Comments From: Institut fur Rekonstruktive Neurobiologie, University Clinic of Bonn; Bonn; Germany.
Population: Caucasian.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; HGNC:613; APOE; Simple; p.Cys130Arg (c.388T>C); ClinVar=VCV000017864; Zygosity=Homozygous; Note=ApoE4 allele (PubMed=29753274).
Disease Alzheimer's disease (NCIt: C2866)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_RM82 (UKBi011-A-1)CVCL_RX83 (UKBi011-A-3)CVCL_RM83 (UKBi011-A-4)
Sex of cell Male
Age at sampling 80Y
Category Induced pluripotent stem cell
Publications

PubMed=29753274; DOI=10.1016/j.scr.2018.04.011
Michael Peitz, Tamara Bechler, Catrin Cornelia Thiele, Monika Veltel, Melanie Bloschies, Klaus Fliessbach, Alfredo Ramirez, Oliver Brustle;
Blood-derived integration-free iPS cell line UKBi011-A from a diagnosed male Alzheimer's disease patient with APOE epsilon4/epsilon4 genotype.
Stem Cell Res. 29:250-253(2018)

Cross-references
Cell line collections (Providers) EBiSC; UKBi011-A
ECACC; 66540594 - Discontinued
Cell line databases/resources hPSCreg; UKBi011-A
Biological sample resources BioSamples; SAMEA104132640
Encyclopedic resources Wikidata; Q54990267
Entry history
Entry creation22-Aug-2017
Last entry update19-Dec-2024
Version number12