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Cellosaurus HML-2 [Human leukemia] (CVCL_RL97)

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Cell line name HML-2 [Human leukemia]
Accession CVCL_RL97
Resource Identification Initiative To cite this cell line use: HML-2 [Human leukemia] (RRID:CVCL_RL97)
Comments Population: Japanese.
Characteristics: CSF2 and KITLG dependent.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Disease Down syndrome (NCIt: C2993)
Myeloid leukemia associated with Down syndrome (NCIt: C43223)
Down syndrome (ORDO: Orphanet_870)
Acute megakaryoblastic leukemia in Down syndrome (ORDO: Orphanet_99887)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_RL96 (HML)
Sex of cell Male
Age at sampling 2Y
Category Cancer cell line
Publications

PubMed=9444944; DOI=10.1016/S0145-2126(97)00086-6
Takehiko Kamijo, Kenichi Koike, Kouichi Takeuchi, Tsukasa Higuchi, Nobukuni Sawai, Toshimi Kikuchi, Haruhiko Tsumura, Hirokazu Akiyama, Tadashi Koike, Eizaburo Ishii, Atsushi Komiyama;
Analysis of synergism between stem cell factor and granulocyte-macrophage colony-stimulating factor on human megakaryoblastic cells: an increase in tyrosine phosphorylation of 145 kDa subunit of c-kit in two-factor combination.
Leuk. Res. 21:1097-1106(1997)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

Cross-references
Encyclopedic resources Wikidata; Q54889936
Polymorphism and mutation databases Cosmic; 787434
Entry history
Entry creation05-Mar-2018
Last entry update29-Jun-2023
Version number7