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Cellosaurus HML (CVCL_RL96)

[Text version]
Cell line name HML
Accession CVCL_RL96
Resource Identification Initiative To cite this cell line use: HML (RRID:CVCL_RL96)
Comments Population: Japanese.
Characteristics: CSF2 dependent.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Disease Down syndrome (NCIt: C2993)
Myeloid leukemia associated with Down syndrome (NCIt: C43223)
Down syndrome (ORDO: Orphanet_870)
Acute megakaryoblastic leukemia in Down syndrome (ORDO: Orphanet_99887)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_RL97 (HML-2 [Human leukemia])CVCL_RL98 (HML/SE)
Sex of cell Male
Age at sampling 2Y
Category Cancer cell line
Publications

PubMed=9444944; DOI=10.1016/S0145-2126(97)00086-6
Takehiko Kamijo, Kenichi Koike, Kouichi Takeuchi, Tsukasa Higuchi, Nobukuni Sawai, Toshimi Kikuchi, Haruhiko Tsumura, Hirokazu Akiyama, Tadashi Koike, Eizaburo Ishii, Atsushi Komiyama;
Analysis of synergism between stem cell factor and granulocyte-macrophage colony-stimulating factor on human megakaryoblastic cells: an increase in tyrosine phosphorylation of 145 kDa subunit of c-kit in two-factor combination.
Leuk. Res. 21:1097-1106(1997)

PubMed=9488639; DOI=10.1046/j.1365-2141.1998.00553.x
Feng Ma, Kenichi Koike, Tsukasa Higuchi, Tatsuya Kinoshita, Kouichi Takeuchi, Hadija Hemed Mwamtemi, Nobukuni Sawai, Takehiko Kamijo, Masaaki Shiohara, Shiro Horie, Shigeyuki Kawa ...Show all 18 authors... , Yumiko Sasaki, Eiko Hidaka, Osamu Yamagami, Tetsuji Yamashita, Tadashi Koike, Eizaburo Ishii, Atsushi Komiyama; Show fewer authors
Establishment of a GM-CSF-dependent megakaryoblastic cell line with the potential to differentiate into an eosinophilic lineage in response to retinoic acids.
Br. J. Haematol. 100:427-435(1998)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

Cross-references
Encyclopedic resources Wikidata; Q54889935
Entry history
Entry creation05-Mar-2018
Last entry update29-Jun-2023
Version number6