Cellosaurus A375-hNIS-Neo/eGFP-Puro (CVCL_QZ71)
Cell line name | A375-hNIS-Neo/eGFP-Puro |
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Accession | CVCL_QZ71 |
Resource Identification Initiative | To cite this cell line use: A375-hNIS-Neo/eGFP-Puro (RRID:CVCL_QZ71) |
Comments | Population: Caucasian. Characteristics: Reporter cell line, transfected with both the LV-hNIS-IRES-Neo and LV-eGFP-PGK-Puro vectors. LV-hNIS-IRES-Neo encodes for human SLC5A5 linked via an internal ribosomal entry site (IRES) to the Neo gene and under control of the spleen focus-forming virus (SFFV) promoter. LV-eGFP-PGK-Puro encodes for eGFP under control of the spleen focus-forming virus (SFFV) promoter and the pac gene under the control of the mouse PGK promoter. Transfected with: HGNC; 11040; SLC5A5. Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP). Transfected with: UniProtKB; P00552; Transposon Tn5 neo. Transfected with: UniProtKB; P13249; S.alboniger pac (PuroR). Derived from site: In situ; Skin; UBERON=UBERON_0002097. |
Sequence variations |
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Disease | Amelanotic melanoma (NCIt: C3802) |
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
Hierarchy | Parent: CVCL_0132 (A-375) |
Sex of cell | Female |
Age at sampling | 54Y |
Category | Cancer cell line |
Cross-references | |
Cell line collections (Providers) | Imanis; CL086 |
Cell line databases/resources | cancercelllines; CVCL_QZ71 |
Encyclopedic resources | Wikidata; Q54606791 |
Entry history | |
Entry creation | 05-Mar-2018 |
Last entry update | 05-Oct-2023 |
Version number | 13 |