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Cellosaurus RMKN-28 (CVCL_QZ55)

[Text version]
Cell line name RMKN-28
Accession CVCL_QZ55
Resource Identification Initiative To cite this cell line use: RMKN-28 (RRID:CVCL_QZ55)
Comments Problematic cell line: Contaminated. Parent cell line (MKN28) has been shown to be a MKN74 derivative.
Population: Japanese.
Selected for resistance to: ChEBI; CHEBI:175901; Gemcitabine (Gemzar).
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations
Disease Gastric tubular adenocarcinoma (NCIt: C5473)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1416 (MKN28)
Sex of cell Male
Age at sampling 37Y
Category Cancer cell line

PubMed=22490663; DOI=10.1016/j.bbrc.2012.03.122
Saiki Y., Yoshino Y., Fujimura H., Manabe T., Kudo Y., Shimada M., Mano N., Nakano T., Lee Y., Shimizu S., Oba S., Fujiwara S., Shimizu H., Chen N., Nezhad Z.K., Jin G., Fukushige S., Sunamura M., Ishida M., Motoi F., Egawa S., Unno M., Horii A.
DCK is frequently inactivated in acquired gemcitabine-resistant human cancer cells.
Biochem. Biophys. Res. Commun. 421:98-104(2012)

Cell line databases/resources cancercelllines; CVCL_QZ55
Encyclopedic resources Wikidata; Q54950673
Entry history
Entry creation05-Mar-2018
Last entry update05-Oct-2023
Version number7