Cellosaurus cell line RMKN-28 (CVCL

Cellosaurus RMKN-28 (CVCL_QZ55)

Cross-references
Cell line name	RMKN-28
Accession	CVCL_QZ55
Resource Identification Initiative	To cite this cell line use: RMKN-28 (RRID:CVCL_QZ55)
Comments	Problematic cell line: Contaminated. Parent cell line (MKN28) has been shown to be a MKN74 derivative. Population: Japanese. Selected for resistance to: ChEBI; CHEBI_175901; Gemcitabine (Gemzar). Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ile251Leu (c.751A>C); ClinVar=VCV000182937; Zygosity=Unspecified (PubMed=22490663).
Disease	Gastric tubular adenocarcinoma (NCIt: C5473)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_1416 (MKN28)
Sex of cell	Male
Age at sampling	37Y
Category	Cancer cell line
Publications	PubMed=22490663; DOI=10.1016/j.bbrc.2012.03.122 Yuriko Saiki, Yuki Yoshino, Hiroko Fujimura, Tatsuya Manabe, Yuki Kudo, Miki Shimada, Nariyasu Mano, Tomohiro Nakano, Yoonha Lee, Shinjiro Shimizu, Shinya Oba ...Show all 23 authors... , Sho Fujiwara, Hideyuki Shimizu, Na Chen, Zhaleh Kashkouli Nezhad, Guo Jin, Shinichi Fukushige, Makoto Sunamura, Masaharu Ishida, Fuyuhiko Motoi, Shinichi Egawa, Michiaki Unno, Akira Horii; Show fewer authors DCK is frequently inactivated in acquired gemcitabine-resistant human cancer cells. Biochem. Biophys. Res. Commun. 421:98-104(2012)
Cell line databases/resources	cancercelllines; CVCL_QZ55
Encyclopedic resources	Wikidata; Q54950673
Entry history
Entry creation	05-Mar-2018
Last entry update	19-Dec-2024
Version number	8