Cellosaurus logo
expasy logo

Cellosaurus RTFK-1 (CVCL_QZ53)

[Text][XML][JSON]
Cell line name RTFK-1
Accession CVCL_QZ53
Resource Identification Initiative To cite this cell line use: RTFK-1 (RRID:CVCL_QZ53)
Comments Population: Japanese.
Selected for resistance to: ChEBI; CHEBI_175901; Gemcitabine (Gemzar).
Misspelling: RTFKK-1; PubMed=22490663; Note=In supplementary figure 2.
Derived from site: In situ; Extrahepatic bile duct; UBERON=UBERON_0003703.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Trp91Ter (c.272G>A); ClinVar=VCV000233650; Zygosity=Homozygous (from parent cell line).
Disease Cholangiocarcinoma (NCIt: C4436)
Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2214 (TFK-1)
Sex of cell Male
Age at sampling 63Y
Category Cancer cell line
Publications

PubMed=22490663; DOI=10.1016/j.bbrc.2012.03.122
Yuriko Saiki, Yuki Yoshino, Hiroko Fujimura, Tatsuya Manabe, Yuki Kudo, Miki Shimada, Nariyasu Mano, Tomohiro Nakano, Yoonha Lee, Shinjiro Shimizu, Shinya Oba ...Show all 23 authors... , Sho Fujiwara, Hideyuki Shimizu, Na Chen, Zhaleh Kashkouli Nezhad, Guo Jin, Shinichi Fukushige, Makoto Sunamura, Masaharu Ishida, Fuyuhiko Motoi, Shinichi Egawa, Michiaki Unno, Akira Horii; Show fewer authors
DCK is frequently inactivated in acquired gemcitabine-resistant human cancer cells.
Biochem. Biophys. Res. Commun. 421:98-104(2012)

Cross-references
Cell line databases/resources cancercelllines; CVCL_QZ53
Encyclopedic resources Wikidata; Q54951396
Entry history
Entry creation05-Mar-2018
Last entry update19-Dec-2024
Version number11