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Cellosaurus HuCC-T1-G100 (CVCL_QZ45)

[Text version]
Cell line name HuCC-T1-G100
Synonyms HuCCT1-G100
Accession CVCL_QZ45
Resource Identification Initiative To cite this cell line use: HuCC-T1-G100 (RRID:CVCL_QZ45)
Comments Population: Japanese.
Selected for resistance to: ChEBI; CHEBI_175901; Gemcitabine (Gemzar).
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7329; MSH6; Simple; p.Lys1358fs*2 (c.4071_4072insGATT); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Homozygous (from parent cell line).
Disease Intrahepatic cholangiocarcinoma (NCIt: C35417)
Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0324 (HuCC-T1)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
Publications

PubMed=21451941; DOI=10.1007/s00534-011-0376-7
Jun Sato, Takashi Kimura, Takuro Saito, Takayuki Anazawa, Akira Kenjo, Yoshihiro Sato, Takao Tsuchiya, Mitsukazu Gotoh;
Gene expression analysis for predicting gemcitabine resistance in human cholangiocarcinoma.
J. Hepatobiliary Pancreat. Sci. 18:700-711(2011)

Cross-references
Cell line databases/resources cancercelllines; CVCL_QZ45
Encyclopedic resources Wikidata; Q54896727
Entry history
Entry creation05-Mar-2018
Last entry update19-Dec-2024
Version number11