Cellosaurus cell line VA-ES-BJ BAF47 (CVCL

Cellosaurus VA-ES-BJ BAF47 (CVCL_QW58)

Cross-references
Cell line name	VA-ES-BJ BAF47
Synonyms	VA-ES-BJ_BAF47; VAESBJ_BAF47
Accession	CVCL_QW58
Resource Identification Initiative	To cite this cell line use: VA-ES-BJ BAF47 (RRID:CVCL_QW58)
Comments	Population: Caucasian. Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:11103; SMARCB1. Omics: Genomics; ChIP-seq; H3K27ac. Omics: Genomics; ChIP-seq; H3K27me3. Omics: Genomics; ChIP-seq; H3K4me3. Omics: Transcriptomics; RNAseq. Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Sequence variations	Mutation; HGNC; HGNC:7773; NF2; Simple; p.Ser87Ter (c.260C>A); Zygosity=Homozygous (from parent cell line).
Disease	Epithelioid sarcoma (NCIt: C3714) Epithelioid sarcoma (ORDO: Orphanet_293202)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_1785 (VA-ES-BJ)
Sex of cell	Male
Age at sampling	41Y
Category	Cancer cell line
Publications	PubMed=28945250; DOI=10.1038/ng.3958; PMCID=PMC5803080 Robert T. Nakayama, John L. Pulice, Alfredo M. Valencia, Matthew J. McBride, Zachary M. McKenzie, Mark A. Gillespie, Wai Lim Ku, Ming-Xiang Teng, Kai-Rong Cui, Robert T. Williams, Seth H. Cassel ...Show all 18 authors... , He Qing, Christian J. Widmer, George Daniel Demetri, Rafael Angel Irizarry, Ke-Ji Zhao, Jeffrey A. Ranish, Cigall Kadoch; Show fewer authors SMARCB1 is required for widespread BAF complex-mediated activation of enhancers and bivalent promoters. Nat. Genet. 49:1613-1623(2017)
Encyclopedic resources	Wikidata; Q54992644
Gene expression databases	GEO; GSM2409700 GEO; GSM2409701 GEO; GSM2409702 GEO; GSM2409703 GEO; GSM2409704 GEO; GSM2409705 GEO; GSM2787359
Entry history
Entry creation	15-Nov-2017
Last entry update	10-Apr-2025
Version number	12