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Cellosaurus L1210/R81 (CVCL_N028)

[Text version]

Cell line name L1210/R81
Synonyms L1210 (R81)
Accession CVCL_N028
Resource Identification Initiative To cite this cell line use: L1210/R81 (RRID:CVCL_N028)
Comments Selected for resistance to: ChEBI; CHEBI:44185; Methotrexate (MTX).
Transformant: ChEBI; CHEBI:34342; 3-methylcholanthrene (3-MC; 20-methylcholanthrene; 20-MC; MCA).
Derived from sampling site: Ascites.
Disease Mouse leukemia (NCIt: C21604)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: DBA/2.
Hierarchy Parent: CVCL_0382 (L1210)
Sex of cell Female
Age at sampling 8M
Category Cancer cell line

Rosowsky A., Forsch R.A., Galivan J., Susten S.S., Freisheim J.H.
Regiospecific gamma-conjugation of methotrexate to poly(L-lysine) Chemical and biological studies.
Mol. Pharmacol. 27:141-147(1985)

Chemistry resources ChEMBL-Cells; CHEMBL3307415
ChEMBL-Targets; CHEMBL614710
Encyclopedic resources Wikidata; Q54900965
Entry history
Entry creation05-Nov-2013
Last entry update02-Jul-2020
Version number10