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Cellosaurus TSU-Pr1-B2 (CVCL_M905)

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Cell line name TSU-Pr1-B2
Accession CVCL_M905
Resource Identification Initiative To cite this cell line use: TSU-Pr1-B2 (RRID:CVCL_M905)
Comments Problematic cell line: Contaminated. Grand-parent cell line (TSU-Pr1) has been shown to be a T24 derivative.
Population: Caucasian; Swedish.
Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
Sequence variations
  • Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).
Disease Bladder carcinoma (NCIt: C4912)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_M904 (TSU-Pr1-B1)
Sex of cell Female
Age at sampling 82Y
Category Cancer cell line
Publications

PubMed=16086232; DOI=10.1007/s10585-005-5141-3
Christine L. Chaffer, Bonnie Dopheide, Daniel R. McCulloch, Allan B. Lee, Jane M. Moseley, Erik W. Thompson, Elizabeth Deborah Williams;
Upregulated MT1-MMP/TIMP-2 axis in the TSU-Pr1-B1/B2 model of metastatic progression in transitional cell carcinoma of the bladder.
Clin. Exp. Metastasis 22:115-125(2005)

Cross-references
Cell line databases/resources cancercelllines; CVCL_M905
Encyclopedic resources Wikidata; Q54973172
Entry history
Entry creation05-Nov-2013
Last entry update19-Dec-2024
Version number17