ID   TSU-Pr1-B2
AC   CVCL_M905
DR   cancercelllines; CVCL_M905
DR   Wikidata; Q54973172
RX   PubMed=16086232;
CC   Problematic cell line: Contaminated. Grand-parent cell line (TSU-Pr1) has been shown to be a T24 derivative.
CC   Population: Caucasian; Swedish.
CC   Sequence variation: Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012600; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr126Ter (c.378C>G); ClinVar=VCV000578988; Zygosity=Homozygous (from parent cell line).
CC   Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255.
DI   NCIt; C4912; Bladder carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_M904 ! TSU-Pr1-B1
SX   Female
AG   82Y
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 19-12-24; Version: 17
//
RX   PubMed=16086232; DOI=10.1007/s10585-005-5141-3;
RA   Chaffer, Christine L.
RA   Dopheide, Bonnie
RA   McCulloch, Daniel R.
RA   Lee, Allan B.
RA   Moseley, Jane M.
RA   Thompson, Erik W.
RA   Williams, Elizabeth Deborah
RT   "Upregulated MT1-MMP/TIMP-2 axis in the TSU-Pr1-B1/B2 model of
RT   metastatic progression in transitional cell carcinoma of the
RT   bladder.";
RL   Clin. Exp. Metastasis 22:115-125(2005).
//