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Cellosaurus T-1 (CVCL_M858)

[Text version]
Cell line name T-1
Synonyms T1
Accession CVCL_M858
Resource Identification Initiative To cite this cell line use: T-1 (RRID:CVCL_M858)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=7394535; PubMed=20143388). Originally thought to originate from the kidney of a 8 year old boy.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00095.
Population: African American.
Doubling time: ~22-24 hours (DOI=10.2172/4683311).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx

PubMed=13545791; DOI=10.1007/BF01241484
van der Veen J., Bots L., Mes A.
Establishment of two human cell strains from kidney and reticulosarcoma in lung.
Arch. Gesamte Virusforsch. 8:230-238(1958)

PubMed=13686930; DOI=10.2307/3570859
Barendsen G.W., Beusker T.L., Vergroesen A.J., Budke L.
Effects of different radiations on human cells in tissue culture. II Biological experiments.
Radiat. Res. 13:841-849(1960)

Todd P.W.
Reversible and irreversible effects of ionizing radiations on the reproductive integrity of mammalian cells cultured in vitro.
Thesis PhD (1964), University of California, United States

PubMed=4288260; DOI=10.1007/BF02097456
Peutz-de Jong M., Mes A., van der Veen J.
Susceptibility of cell lines of primate and nonprimate origin to certain human viruses.
Antonie Van Leeuwenhoek 32:162-169(1966)

PubMed=5660764; DOI=10.1016/0027-5107(68)90090-0
Todd P.W.
Defective mammalian cells isolated from X-irradiated cultures.
Mutat. Res. 5:173-183(1968)

PubMed=1167420; DOI=10.2307/3574046
Todd P.W.
Heavy-ion irradiation of human and Chinese hamster cells in vitro.
Radiat. Res. 61:288-297(1975)

PubMed=7394535; DOI=10.1126/science.7394535
Nelson-Rees W.A., Flandermeyer R.R., Daniels D.W.
T-1 cells are HeLa and not of normal human kidney origin.
Science 209:719-720(1980)

Gold M.
A conspiracy of cells. One woman's immortal legacy and the medical scandal it caused.
(In) ISBN 9780887060991; pp.1-171; State University of New York Press; Albany (1986)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Biological sample resources BioSample; SAMN03151761
Encyclopedic resources Wikidata; Q54971324
Entry history
Entry creation05-Nov-2013
Last entry update30-Jan-2024
Version number19