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Cellosaurus MM-M1 (CVCL_M547)

[Text version]
Cell line name MM-M1
Synonyms MM.M1; MMM1
Accession CVCL_M547
Resource Identification Initiative To cite this cell line use: MM-M1 (RRID:CVCL_M547)
Comments Population: Japanese.
Characteristics: Produces IgG kappa.
Omics: Transcriptomics; RNAseq.
Omics: Variations; Array-based CGH.
Cell type: Plasma cell; CL=CL_0000786.
Sequence variations
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
Web pages Info; Keats Lab; -; https://www.keatslab.org/myeloma-cell-lines
Publications

PubMed=1720489; DOI=10.1016/0145-2126(91)90110-f
Akira Suzuki, Takayuki Takahashi, Yoshiaki Okuno, Manabu Fukumoto, Hiroyasu Fukui, Yasuo Koishihara, Yoshiaki Ohsugi, Yohichiro Ohno, Hiroo Imura;
Estimation of interleukin 6 production by reverse transcriptase-polymerase chain reaction in four human myeloma cell lines.
Leuk. Res. 15:1043-1050(1991)

PubMed=8695815; DOI=10.1182/blood.V88.2.674.bloodjournal882674
Marta Chesi, Peter Leif Bergsagel, Leslie A. Brents, Carissa M. Smith, Daniela S. Gerhard, Walter Michael Kuehl;
Dysregulation of cyclin D1 by translocation into an IgH gamma switch region in two multiple myeloma cell lines.
Blood 88:674-681(1996)

PubMed=8943038; DOI=10.1073/pnas.93.24.13931; PMCID=PMC19472
Peter Leif Bergsagel, Marta Chesi, Elena Nardini, Leslie A. Brents, Suzanne Lee Kirby, Walter Michael Kuehl;
Promiscuous translocations into immunoglobulin heavy chain switch regions in multiple myeloma.
Proc. Natl. Acad. Sci. U.S.A. 93:13931-13936(1996)

DOI=10.1007/0-306-46877-8_4
Helena Jernberg-Wiklund, Kenneth Nilsson;
Multiple myeloma cell lines.
(In book chapter) Human cell culture. Vol. 3. Cancer cell lines part 3; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.81-155; Kluwer Academic Publishers; New York; USA (2000)

PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2
Hans Gunther Drexler, Yoshinobu Matsuo;
Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia.
Leuk. Res. 24:681-703(2000)

PubMed=17692805; DOI=10.1016/j.ccr.2007.07.003; PMCID=PMC2083698
Jonathan J. Keats, Rafael Fonseca, Marta Chesi, Roelandt Schop, Angela Baker, Wee-Joo Chng, Scott Van Wier, Rodger Tiedemann, Chang-Xin Shi, Michael Sebag, Esteban Braggio ...Show all 30 authors... , Travis Henry, Yuan-Xiao Zhu, Homer Fogle, Tammy L. Price-Troska, Gregory J. Ahmann, Catherine Mancini, Leslie A. Brents, Shaji K. Kumar, Philip Robert Greipp, Angela Dispenzieri, Barb Bryant, George Mulligan, Laurakay Bruhn, Michael T. Barrett, Riccardo Valdez, Jeffrey M. Trent, A. Keith Stewart, John D. Carpten, Peter Leif Bergsagel; Show fewer authors
Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.
Cancer Cell 12:131-144(2007)

CLPUB00604
Sharon Chow;
Targeted capture and sequencing of immunoglobulin rearrangements in multiple myeloma to enable detection of minimal residual disease.
Thesis MSc (2017); University of Toronto; Toronto; Canada

PubMed=32123307; DOI=10.1038/s41375-020-0785-1; PMCID=PMC7483300
Vishesh Sarin, Katharine Yu, Ian D. Ferguson, Olivia Gugliemini, Matthew A. Nix, Byron Hann, Marina Sirota, Arun P. Wiita;
Evaluating the efficacy of multiple myeloma cell lines as models for patient tumors via transcriptomic correlation analysis.
Leukemia 34:2754-2765(2020)

Cross-references
Encyclopedic resources Wikidata; Q54906021
Polymorphism and mutation databases Cosmic; 2081398
Cosmic; 2302407
Entry history
Entry creation05-Nov-2013
Last entry update14-Aug-2025
Version number17