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Cellosaurus TH [Human plasma cell myeloma] (CVCL_M528)

[Text version]
Cell line name TH [Human plasma cell myeloma]
Accession CVCL_M528
Resource Identification Initiative To cite this cell line use: TH [Human plasma cell myeloma] (RRID:CVCL_M528)
Comments Characteristics: Produces IgG3 kappa.
Doubling time: ~24 hours (PubMed=1958480).
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Plasma cell; CL=CL_0000786.
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 32Y
Category Cancer cell line
Publications

PubMed=1958480; DOI=10.1111/j.1365-2141.1991.tb04526.x
Stephanie S. Weinreich, Albert Ernst Gustaaf Kreutzwendedich von dem Borne, Rene A.W. van Lier, Constance Alide Feltkamp, Rosalyn M. Slater, Mieke R. Wester, Wim P. Zeijlemaker;
Characterization of a human plasmacytoma line.
Br. J. Haematol. 79:226-234(1991)

PubMed=8943038; DOI=10.1073/pnas.93.24.13931; PMCID=PMC19472
Peter Leif Bergsagel, Marta Chesi, Elena Nardini, Leslie A. Brents, Suzanne Lee Kirby, Walter Michael Kuehl;
Promiscuous translocations into immunoglobulin heavy chain switch regions in multiple myeloma.
Proc. Natl. Acad. Sci. U.S.A. 93:13931-13936(1996)

PubMed=10087940; DOI=10.1016/S0165-4608(98)00157-5
Jeroen Kuipers, Jan Willem Vaandrager, Danielle Olde Weghuis, Peter Lees Pearson, Jacques Scheres, Henk Martinus Lokhorst, Hans Cornelius Clevers, Bert J.E.G. Bast;
Fluorescence in situ hybridization analysis shows the frequent occurrence of 14q32.3 rearrangements with involvement of immunoglobulin switch regions in myeloma cell lines.
Cancer Genet. Cytogenet. 109:99-107(1999)

DOI=10.1007/0-306-46877-8_4
Helena Jernberg-Wiklund, Kenneth Nilsson;
Multiple myeloma cell lines.
(In book chapter) Human cell culture. Vol. 3. Cancer cell lines part 3; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.81-155; Kluwer Academic Publishers; New York; USA (2000)

PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2
Hans Gunther Drexler, Yoshinobu Matsuo;
Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia.
Leuk. Res. 24:681-703(2000)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=11157491; DOI=10.1182/blood.V97.3.729
Marta Chesi, Leslie A. Brents, Sarah A. Ely, Carlos Bais, Davide F. Robbiani, Enrique A. Mesri, Walter Michael Kuehl, Peter Leif Bergsagel;
Activated fibroblast growth factor receptor 3 is an oncogene that contributes to tumor progression in multiple myeloma.
Blood 97:729-736(2001)

Cross-references
Encyclopedic resources Wikidata; Q54972277
Polymorphism and mutation databases Cosmic; 720794
Cosmic; 760395
Cosmic; 2302419
Entry history
Entry creation05-Nov-2013
Last entry update14-Aug-2025
Version number16