ID   TH [Human plasma cell myeloma]
AC   CVCL_M528
DR   Cosmic; 720794
DR   Cosmic; 760395
DR   Cosmic; 2302419
DR   Wikidata; Q54972277
RX   DOI=10.1007/0-306-46877-8_4;
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=1958480;
RX   PubMed=8943038;
RX   PubMed=10087940;
RX   PubMed=10936422;
RX   PubMed=11157491;
CC   Characteristics: Produces IgG3 kappa.
CC   Doubling time: ~24 hours (PubMed=1958480).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
CC   Cell type: Plasma cell; CL=CL_0000786.
DI   NCIt; C3242; Plasma cell myeloma
DI   ORDO; Orphanet_29073; Multiple myeloma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   32Y
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 14-08-25; Version: 16
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RX   DOI=10.1007/0-306-46877-8_4;
RA   Jernberg-Wiklund, Helena
RA   Nilsson, Kenneth
RT   "Multiple myeloma cell lines.";
RL   (In book chapter) Human cell culture. Vol. 3. Cancer cell lines part 3; Masters, John R.W. & Palsson, Bernhard Orn (eds.); pp.81-155; Kluwer Academic Publishers; New York; USA (2000).
//
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler, Hans Gunther
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).
//
RX   PubMed=1958480; DOI=10.1111/j.1365-2141.1991.tb04526.x;
RA   Weinreich, Stephanie S.
RA   von dem Borne, Albert Ernst Gustaaf Kreutzwendedich
RA   van Lier, Rene A.W.
RA   Feltkamp, Constance Alide
RA   Slater, Rosalyn M.
RA   Wester, Mieke R.
RA   Zeijlemaker, Wim P.
RT   "Characterization of a human plasmacytoma line.";
RL   Br. J. Haematol. 79:226-234(1991).
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RX   PubMed=8943038; DOI=10.1073/pnas.93.24.13931; PMCID=PMC19472;
RA   Bergsagel, Peter Leif
RA   Chesi, Marta
RA   Nardini, Elena
RA   Brents, Leslie A.
RA   Kirby, Suzanne Lee
RA   Kuehl, Walter Michael
RT   "Promiscuous translocations into immunoglobulin heavy chain switch
RT   regions in multiple myeloma.";
RL   Proc. Natl. Acad. Sci. U.S.A. 93:13931-13936(1996).
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RX   PubMed=10087940; DOI=10.1016/S0165-4608(98)00157-5;
RA   Kuipers, Jeroen
RA   Vaandrager, Jan Willem
RA   Weghuis, Danielle Olde
RA   Pearson, Peter Lees
RA   Scheres, Jacques
RA   Lokhorst, Henk Martinus
RA   Clevers, Hans Cornelius
RA   Bast, Bert J.E.G.
RT   "Fluorescence in situ hybridization analysis shows the frequent
RT   occurrence of 14q32.3 rearrangements with involvement of
RT   immunoglobulin switch regions in myeloma cell lines.";
RL   Cancer Genet. Cytogenet. 109:99-107(1999).
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RX   PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2;
RA   Drexler, Hans Gunther
RA   Matsuo, Yoshinobu
RT   "Malignant hematopoietic cell lines: in vitro models for the study of
RT   multiple myeloma and plasma cell leukemia.";
RL   Leuk. Res. 24:681-703(2000).
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RX   PubMed=11157491; DOI=10.1182/blood.V97.3.729;
RA   Chesi, Marta
RA   Brents, Leslie A.
RA   Ely, Sarah A.
RA   Bais, Carlos
RA   Robbiani, Davide F.
RA   Mesri, Enrique A.
RA   Kuehl, Walter Michael
RA   Bergsagel, Peter Leif
RT   "Activated fibroblast growth factor receptor 3 is an oncogene that
RT   contributes to tumor progression in multiple myeloma.";
RL   Blood 97:729-736(2001).
//