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Cellosaurus KAS-6/2 (CVCL_M524)

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Cell line name KAS-6/2
Accession CVCL_M524
Resource Identification Initiative To cite this cell line use: KAS-6/2 (RRID:CVCL_M524)
Comments Characteristics: Produces IgG kappa.
Characteristics: IL6 dependent.
Cell type: Plasma cell; CL=CL_0000786.
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_9544 ! KAS-6/1
Sex of cell Female
Age at sampling 56Y
Category Cancer cell line
Web pages Info; Keats Lab; -; https://www.keatslab.org/myeloma-cell-lines
Publications

PubMed=8656685
Jennifer J. Westendorf, Gregory J. Ahmann, Philip Robert Greipp, Thomas E. Witzig, John Anthony Lust, Diane F. Jelinek;
Establishment and characterization of three myeloma cell lines that demonstrate variable cytokine responses and abilities to produce autocrine interleukin-6.
Leukemia 10:866-876(1996)

PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2
Hans Gunther Drexler, Yoshinobu Matsuo;
Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia.
Leuk. Res. 24:681-703(2000)

DOI=10.1182/blood.V112.11.2732.2732
Jonathan J. Keats, Bonnie K. Arendt, Esteban Braggio, Michael T. Barrett, Tammy L. Price-Troska, Rafael Fonseca, Peter Leif Bergsagel, Diane F. Jelinek;
Comparison of multiple myeloma donor patient samples and derived cell lines identifies a confirmed hyperdiploid myeloma cell line and demonstrates remarkable genetic similarity between cell lines and patient samples.
Blood 112 Suppl. 1:2732a-2732a(2008)

Cross-references
Encyclopedic resources Wikidata; Q54899507
Entry history
Entry creation05-Nov-2013
Last entry update14-Aug-2025
Version number13