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Cellosaurus MEF-1 [Human myeloma] (CVCL_M515)

[Text version]
Cell line name MEF-1 [Human myeloma]
Accession CVCL_M515
Resource Identification Initiative To cite this cell line use: MEF-1 [Human myeloma] (RRID:CVCL_M515)
Comments Population: Japanese.
Characteristics: Produces IgG kappa.
Doubling time: ~36 hours (PubMed=10223569).
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ile255_Leu257delinsSer (c.763_768del6); Zygosity=Unspecified (PubMed=10223569).
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 67Y
Category Cancer cell line
Publications

PubMed=10223569; DOI=10.1002/(SICI)1097-0142(19990415)85:8<1750::AID-CNCR15>3.0.CO;2-5
Yufu Y., Goto T., Choi I., Uike N., Kozuru M., Ohshima K.-i., Taniguchi T., Motokura T., Yatabe Y., Nakamura S.
A new multiple myeloma cell line, MEF-1, possesses cyclin D1 overexpression and the p53 mutation.
Cancer 85:1750-1757(1999)

DOI=10.1007/0-306-46877-8_4
Jernberg-Wiklund H., Nilsson K.
Multiple myeloma cell lines.
(In book chapter) Human cell culture. Vol. 3. Cancer cell lines part 3; Masters J.R.W., Palsson B.O. (eds.); pp.81-155; Kluwer Academic Publishers; New York; USA (2000)

PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2
Drexler H.G., Matsuo Y.
Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia.
Leuk. Res. 24:681-703(2000)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

Cross-references
Encyclopedic resources Wikidata; Q54905028
Polymorphism and mutation databases IARC_TP53; 10417
Entry history
Entry creation05-Nov-2013
Last entry update19-Dec-2024
Version number15