ID   MEF-1 [Human myeloma]
AC   CVCL_M515
DR   IARC_TP53; 10417
DR   Wikidata; Q54905028
RX   DOI=10.1007/0-306-46877-8_4;
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=10223569;
RX   PubMed=10936422;
CC   Population: Japanese.
CC   Characteristics: Produces IgG kappa.
CC   Doubling time: ~36 hours (PubMed=10223569).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ile255_Leu257delinsSer (c.763_768del6); Zygosity=Unspecified (PubMed=10223569).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
CC   Cell type: B-cell; CL=CL_0000236.
DI   NCIt; C3242; Plasma cell myeloma
DI   ORDO; Orphanet_29073; Multiple myeloma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   67Y
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 19-12-24; Version: 15
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RX   DOI=10.1007/0-306-46877-8_4;
RA   Jernberg-Wiklund H., Nilsson K.;
RT   "Multiple myeloma cell lines.";
RL   (In book chapter) Human cell culture. Vol. 3. Cancer cell lines part 3; Masters J.R.W., Palsson B.O. (eds.); pp.81-155; Kluwer Academic Publishers; New York; USA (2000).
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RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler H.G.;
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).
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RX   PubMed=10223569; DOI=10.1002/(SICI)1097-0142(19990415)85:8<1750::AID-CNCR15>3.0.CO;2-5;
RA   Yufu Y., Goto T., Choi I., Uike N., Kozuru M., Ohshima K.-i.,
RA   Taniguchi T., Motokura T., Yatabe Y., Nakamura S.;
RT   "A new multiple myeloma cell line, MEF-1, possesses cyclin D1
RT   overexpression and the p53 mutation.";
RL   Cancer 85:1750-1757(1999).
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RX   PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2;
RA   Drexler H.G., Matsuo Y.;
RT   "Malignant hematopoietic cell lines: in vitro models for the study of
RT   multiple myeloma and plasma cell leukemia.";
RL   Leuk. Res. 24:681-703(2000).
//