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Cellosaurus NOP-1 (CVCL_M503)

[Text version]
Cell line name NOP-1
Synonyms NOP1
Accession CVCL_M503
Resource Identification Initiative To cite this cell line use: NOP-1 (RRID:CVCL_M503)
Comments Population: Japanese.
Characteristics: Produces IgA kappa.
Doubling time: 36 hours (CelloPub=CLPUB00090).
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Plasma cell; CL=CL_0000786.
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

CLPUB00090
Michinori Ogura, Ryuzo Ueda, Tomohiro Takeo, Tsuneo Morishima, Norio Hirabayashi, Hidehiko Saito;
Establishment and characterization of a novel human IgA-kappa myeloma cell line (NOP-1) with CD4 antigen in vitro and in vivo.
Blood 74 Suppl. 1:81a.299-81a.299(1989)

PubMed=9737686; DOI=10.1038/sj.leu.2401112
Wen-Ji Zhang, Kazunori Ohnishi, Kazuyuki Shigeno, Shinya Fujisawa, Kensuke Naito, Satoki Nakamura, Kenzo Takeshita, Akihiro Takeshita, Ryuzo Ohno;
The induction of apoptosis and cell cycle arrest by arsenic trioxide in lymphoid neoplasms.
Leukemia 12:1383-1391(1998)

PubMed=9738977; DOI=10.1111/j.1349-7006.1998.tb03275.x; PMCID=PMC5921886
Jun Takizawa, Ritsuro Suzuki, Hiroyuki Kuroda, Atae Utsunomiya, Yoshitoyo Kagami, Tatsuroh Joh, Yoshifusa Aizawa, Ryuzo Ueda, Masao Seto;
Expression of the TCL1 gene at 14q32 in B-cell malignancies but not in adult T-cell leukemia.
Jpn. J. Cancer Res. 89:712-718(1998)

PubMed=10557056; DOI=10.1038/sj.leu.2401563
S. Yoshida, Naozo Nakazawa, S. Iida, Yoshihito Hayami, S. Sato, Atsushi Wakita, S. Shimizu, Masafumi Taniwaki, R. Ueda;
Detection of MUM1/IRF4-IgH fusion in multiple myeloma.
Leukemia 13:1812-1816(1999)

PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2
Hans Gunther Drexler, Yoshinobu Matsuo;
Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia.
Leuk. Res. 24:681-703(2000)

PubMed=11429052; DOI=10.1111/j.1349-7006.2001.tb01142.x; PMCID=PMC5926752
Ichiro Hanamura, Shinsuke Iida, Yumiko Akano, Yoshihito Hayami, Miyuki Kato, Kazuhisa Miura, Shinsuke Harada, Shogo Banno, Atsushi Wakita, Hitoshi Kiyoi, Tomoki Naoe ...Show all 16 authors... , Shiro Shimizu, Shin-ichi Sonta, Masakazu Nitta, Masafumi Taniwaki, Ryuzo Ueda; Show fewer authors
Ectopic expression of MAFB gene in human myeloma cells carrying (14;20)(q32;q11) chromosomal translocations.
Jpn. J. Cancer Res. 92:638-644(2001)

PubMed=12886255; DOI=10.1038/sj.leu.2403026
Yoshihito Hayami, S. Iida, Naozo Nakazawa, Ichiro Hanamura, M. Kato, H. Komatsu, Ikuo Miura, Bhavana J. Dave, Warren G. Sanger, B. Lim, Masafumi Taniwaki, R. Ueda;
Inactivation of the E3/LAPTm5 gene by chromosomal rearrangement and DNA methylation in human multiple myeloma.
Leukemia 17:1650-1657(2003)

PubMed=17229644; DOI=10.3324/haematol.10300
Takaomi Sanda, Shinsuke Iida, Satoshi Kayukawa, Ryuzo Ueda;
Induction of class II major histocompatibility complex expression in human multiple myeloma cells by retinoid.
Haematologica 92:115-120(2007)

Cross-references
Encyclopedic resources Wikidata; Q54930902
Entry history
Entry creation05-Nov-2013
Last entry update14-Aug-2025
Version number15