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Cellosaurus NCU-MM-1 (CVCL_M492)

[Text version]
Cell line name NCU-MM-1
Synonyms NCU-MM1; Nagoya City University-Multiple Myeloma-1
Accession CVCL_M492
Resource Identification Initiative To cite this cell line use: NCU-MM-1 (RRID:CVCL_M492)
Comments Population: Japanese.
Characteristics: Produces IgG kappa.
Doubling time: ~48 hours (PubMed=10979215).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: Plasma cell; CL=CL_0000786.
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 66Y
Category Cancer cell line
Publications

PubMed=10979215
Shinsuke Iida, Ichiro Hanamura, Taisei Suzuki, Takeshi Kamiya, Miyuki Kato, Yoshihito Hayami, Kazuhisa Miura, Shinsuke Harada, Kazuya Tsuboi, Atsushi Wakita, Yumiko Akano ...Show all 14 authors... , Masafumi Taniwaki, Masakazu Nitta, Ryuzo Ueda; Show fewer authors
A novel human multiple myeloma-derived cell line, NCU-MM-1, carrying t(2;11)(q11;q23) and t(8;22)(q24;q11) chromosomal translocations with overexpression of c-Myc protein.
Int. J. Hematol. 72:85-91(2000)

PubMed=11429052; DOI=10.1111/j.1349-7006.2001.tb01142.x; PMCID=PMC5926752
Ichiro Hanamura, Shinsuke Iida, Yumiko Akano, Yoshihito Hayami, Miyuki Kato, Kazuhisa Miura, Shinsuke Harada, Shogo Banno, Atsushi Wakita, Hitoshi Kiyoi, Tomoki Naoe ...Show all 16 authors... , Shiro Shimizu, Shin-ichi Sonta, Masakazu Nitta, Masafumi Taniwaki, Ryuzo Ueda; Show fewer authors
Ectopic expression of MAFB gene in human myeloma cells carrying (14;20)(q32;q11) chromosomal translocations.
Jpn. J. Cancer Res. 92:638-644(2001)

PubMed=12886255; DOI=10.1038/sj.leu.2403026
Yoshihito Hayami, S. Iida, Naozo Nakazawa, Ichiro Hanamura, M. Kato, H. Komatsu, Ikuo Miura, Bhavana J. Dave, Warren G. Sanger, B. Lim, Masafumi Taniwaki, R. Ueda;
Inactivation of the E3/LAPTm5 gene by chromosomal rearrangement and DNA methylation in human multiple myeloma.
Leukemia 17:1650-1657(2003)

PubMed=17171682; DOI=10.1002/gcc.20404
Luigia Lombardi, Giulia Poretti, Michela Mattioli, Sonia Fabris, Luca Agnelli, Silvio Bicciato, Ivo Kwee, Andrea Rinaldi, Domenica Ronchetti, Donata Verdelli, Giorgio Lambertenghi-Deliliers ...Show all 13 authors... , Francesco Bertoni, Antonino Neri; Show fewer authors
Molecular characterization of human multiple myeloma cell lines by integrative genomics: insights into the biology of the disease.
Genes Chromosomes Cancer 46:226-238(2007)

Cross-references
Cell line collections (Providers) ABM; T8055
Encyclopedic resources Wikidata; Q54908295
Gene expression databases GEO; GSM143351
Entry history
Entry creation05-Nov-2013
Last entry update14-Aug-2025
Version number15