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Cellosaurus NCU-MM-1 (CVCL_M492)

[Text version]
Cell line name NCU-MM-1
Synonyms NCU-MM1; Nagoya City University-Multiple Myeloma-1
Accession CVCL_M492
Resource Identification Initiative To cite this cell line use: NCU-MM-1 (RRID:CVCL_M492)
Comments Population: Japanese.
Characteristics: Produces IgG kappa.
Doubling time: ~48 hours (PubMed=10979215).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 66Y
Category Cancer cell line
Publications

PubMed=10979215
Iida S., Hanamura I., Suzuki T., Kamiya T., Kato M., Hayami Y., Miura K., Harada S., Tsuboi K., Wakita A., Akano Y., Taniwaki M., Nitta M., Ueda R.
A novel human multiple myeloma-derived cell line, NCU-MM-1, carrying t(2;11)(q11;q23) and t(8;22)(q24;q11) chromosomal translocations with overexpression of c-Myc protein.
Int. J. Hematol. 72:85-91(2000)

PubMed=11429052; DOI=10.1111/j.1349-7006.2001.tb01142.x; PMCID=PMC5926752
Hanamura I., Iida S., Akano Y., Hayami Y., Kato M., Miura K., Harada S., Banno S., Wakita A., Kiyoi H., Naoe T., Shimizu S., Sonta S.-i., Nitta M., Taniwaki M., Ueda R.
Ectopic expression of MAFB gene in human myeloma cells carrying (14;20)(q32;q11) chromosomal translocations.
Jpn. J. Cancer Res. 92:638-644(2001)

PubMed=12886255; DOI=10.1038/sj.leu.2403026
Hayami Y., Iida S., Nakazawa N., Hanamura I., Kato M., Komatsu H., Miura I., Dave B.J., Sanger W.G., Lim B., Taniwaki M., Ueda R.
Inactivation of the E3/LAPTm5 gene by chromosomal rearrangement and DNA methylation in human multiple myeloma.
Leukemia 17:1650-1657(2003)

PubMed=17171682; DOI=10.1002/gcc.20404
Lombardi L., Poretti G., Mattioli M., Fabris S., Agnelli L., Bicciato S., Kwee I., Rinaldi A., Ronchetti D., Verdelli D., Lambertenghi-Deliliers G., Bertoni F., Neri A.
Molecular characterization of human multiple myeloma cell lines by integrative genomics: insights into the biology of the disease.
Genes Chromosomes Cancer 46:226-238(2007)

Cross-references
Cell line collections (Providers) ABM; T8055
Encyclopedic resources Wikidata; Q54908295
Gene expression databases GEO; GSM143351
Entry history
Entry creation05-Nov-2013
Last entry update10-Apr-2025
Version number14