ID   NCU-MM-1
AC   CVCL_M492
SY   NCU-MM1; Nagoya City University-Multiple Myeloma-1
DR   ABM; T8055
DR   GEO; GSM143351
DR   Wikidata; Q54908295
RX   PubMed=10979215;
RX   PubMed=11429052;
RX   PubMed=12886255;
RX   PubMed=17171682;
CC   Population: Japanese.
CC   Characteristics: Produces IgG kappa.
CC   Doubling time: ~48 hours (PubMed=10979215).
CC   Omics: Transcriptomics; Microarray.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: B-cell; CL=CL_0000236.
DI   NCIt; C3242; Plasma cell myeloma
DI   ORDO; Orphanet_29073; Multiple myeloma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   66Y
CA   Cancer cell line
DT   Created: 05-11-13; Last updated: 10-04-25; Version: 14
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RX   PubMed=10979215;
RA   Iida S., Hanamura I., Suzuki T., Kamiya T., Kato M., Hayami Y.,
RA   Miura K., Harada S., Tsuboi K., Wakita A., Akano Y., Taniwaki M.,
RA   Nitta M., Ueda R.;
RT   "A novel human multiple myeloma-derived cell line, NCU-MM-1, carrying
RT   t(2;11)(q11;q23) and t(8;22)(q24;q11) chromosomal translocations with
RT   overexpression of c-Myc protein.";
RL   Int. J. Hematol. 72:85-91(2000).
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RX   PubMed=11429052; DOI=10.1111/j.1349-7006.2001.tb01142.x; PMCID=PMC5926752;
RA   Hanamura I., Iida S., Akano Y., Hayami Y., Kato M., Miura K.,
RA   Harada S., Banno S., Wakita A., Kiyoi H., Naoe T., Shimizu S.,
RA   Sonta S.-i., Nitta M., Taniwaki M., Ueda R.;
RT   "Ectopic expression of MAFB gene in human myeloma cells carrying
RT   (14;20)(q32;q11) chromosomal translocations.";
RL   Jpn. J. Cancer Res. 92:638-644(2001).
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RX   PubMed=12886255; DOI=10.1038/sj.leu.2403026;
RA   Hayami Y., Iida S., Nakazawa N., Hanamura I., Kato M., Komatsu H.,
RA   Miura I., Dave B.J., Sanger W.G., Lim B., Taniwaki M., Ueda R.;
RT   "Inactivation of the E3/LAPTm5 gene by chromosomal rearrangement and
RT   DNA methylation in human multiple myeloma.";
RL   Leukemia 17:1650-1657(2003).
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RX   PubMed=17171682; DOI=10.1002/gcc.20404;
RA   Lombardi L., Poretti G., Mattioli M., Fabris S., Agnelli L.,
RA   Bicciato S., Kwee I., Rinaldi A., Ronchetti D., Verdelli D.,
RA   Lambertenghi-Deliliers G., Bertoni F., Neri A.;
RT   "Molecular characterization of human multiple myeloma cell lines by
RT   integrative genomics: insights into the biology of the disease.";
RL   Genes Chromosomes Cancer 46:226-238(2007).
//