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Cellosaurus KKU-213C (CVCL_M260)

[Text version]
Cell line name KKU-213C
Synonyms KKU-M156; KKUM156; M156; KKU-156
Accession CVCL_M260
Resource Identification Initiative To cite this cell line use: KKU-213C (RRID:CVCL_M260)
Comments Problematic cell line: Contaminated. Shown to be a KKU-213A derivative (PubMed=32207095 and JCRB web site).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00591.
Population: Southeast Asian; Thai.
Doubling time: 25.6 +- 0.2 hours (PubMed=32207095).
Karyotypic information: Has lost chromosome Y.
Omics: Transcriptome analysis by microarray.
Caution: After JCRB found out that KKU-M156 and KKU-M214 were derived from KKU-M213, these three cell lines were renamed by the lab which established them: KKU-M213 became KKU-213A, KKU-M214 became KKU-M213B and KKU-M156 became KKU-M213C (PubMed=32207095).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly13Cys (c.37G>T); ClinVar=VCV000045123; Zygosity=Unspecified (from parent cell line).
Disease Intrahepatic cholangiocarcinoma (NCIt: C35417)
Opisthorchis viverrini-related cholangiocarcinoma (NCIt: C27769)
Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_M261 (KKU-213A)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): PubMed=32207095


Run an STR similarity search on this cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx

PubMed=15884115; DOI=10.3748/wjg.v11.i18.2748
Tepsiri N., Chaturat L., Sripa B., Namwat W., Wongkham S., Bhudhisawasdi V., Tassaneeyakul W.
Drug sensitivity and drug resistance profiles of human intrahepatic cholangiocarcinoma cell lines.
World J. Gastroenterol. 11:2748-2753(2005)

Panichakul T., Intachote P., Wongkajornsilp A., Sripa B., Sirisinha S.
Triptolide sensitizes resistant cholangiocarcinoma cells to TRAIL-induced apoptosis.
Anticancer Res. 26:259-265(2006)

PubMed=20493868; DOI=10.1016/j.ijpara.2010.05.002
Yonglitthipagon P., Pairojkul C., Chamgramol Y., Mulvenna J., Sripa B.
Up-regulation of annexin A2 in cholangiocarcinoma caused by Opisthorchis viverrini and its implication as a prognostic marker.
Int. J. Parasitol. 40:1203-1212(2010)

PubMed=21871105; DOI=10.1186/1476-4598-10-102
Obchoei S., Weakley S.M., Wongkham S., Wongkham C., Sawanyawisuth K., Yao Q.-Z., Chen C.-Y.
Cyclophilin A enhances cell proliferation and tumor growth of liver fluke-associated cholangiocarcinoma.
Mol. Cancer 10:102.1-102.15(2011)

PubMed=22926522; DOI=10.1038/onc.2012.382
Kunkeaw N., Jeon S.H., Lee K., Johnson B.H., Tanasanvimon S., Javle M., Pairojkul C., Chamgramol Y., Wongfieng W., Gong B., Leelayuwat C., Lee Y.S.
Cell death/proliferation roles for nc886, a non-coding RNA, in the protein kinase R pathway in cholangiocarcinoma.
Oncogene 32:3722-3731(2013)

PubMed=31077409; DOI=10.1002/hep.30704
Sittithumcharee G., Suppramote O., Vaeteewoottacharn K., Sirisuksakun C., Jamnongsong S., Laphanuwat P., Suntiparpluacha M., Matha A., Chusorn P., Buraphat P., Kakanaporn C., Charngkaew K., Silsirivanit A., Korphaisarn K., Limsrichamrern S., Tripatara P., Pairojkul C., Wongkham S., Sampattavanich S., Okada S., Jirawatnotai S.
Dependency of cholangiocarcinoma on cyclin D-dependent kinase activity.
Hepatology 70:1614-1630(2019)

PubMed=32207095; DOI=10.1007/s13577-020-00334-w
Sripa B., Seubwai W., Vaeteewoottacharn K., Sawanyawisuth K., Silsirivanit A., Kaewkong W., Muisuk K., Dana P., Phoomak C., Lert-itthiporn W., Luvira V., Pairojkul C., Teh B.T., Wongkham S., Okada S., Chamgramol Y.
Functional and genetic characterization of three cell lines derived from a single tumor of an Opisthorchis viverrini-associated cholangiocarcinoma patient.
Hum. Cell 33:695-708(2020)

PubMed=35640676; DOI=10.1016/j.ajpath.2022.05.007
Isidan A., Yenigun A., Soma D., Aksu E., Lopez K., Park Y., Cross-Najafi A., Li P., Kundu D., House M.G., Chakraborty S., Glaser S., Kennedy L., Francis H., Zhang W.-J., Alpini G.D., Ekser B.
Development and characterization of human primary cholangiocarcinoma cell lines.
Am. J. Pathol. 192:1200-1217(2022)

Cell line collections (Providers) JCRB; JCRB1561 - Discontinued
Encyclopedic resources Wikidata; Q54900007
Entry history
Entry creation05-Nov-2013
Last entry update29-Jun-2023
Version number16